Products with Inhibitors Bioactivity

Explore BioCrick products associated with Inhibitors biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN4883	Isodiospyrin
1. Isodiospyrin is a novel human DNA topoisomerase I inhibitor, it exhibits cytotoxic activity to tumor cell lines. 2. Isodiospyrin has antibacterial activity, the minimum inhibitory concentrations (MICs) against Gram-positive bacteria ranged from 0.78 to 50 microg/mL. 3. Isodiospyrin shows high antifungal activity against P. obscurans at 30uM with 81.4% growth inhibition, and moderate activity against P. viticola (36.6%).
BCN4887	13(18)-Oleanen-3-one
1. δ-Amyrone(13(18)-Oleanen-3-one), a specific inhibitor of cyclooxygenase-2, possesses anti-inflammatory effects, which may be relevant to the regulation of COX-2. 2. δ-Amyrone has protective activity on LPS-induced endotoxic shock, which is attributed to reducing NO production and mediating the pro-inflammatory cytokines, inhibited NF-κB expression. 3. δ-Amyrone exerts its protective effect on experimental gastric ulcer by inhibiting NF-κB signaling pathways, which subsequently reduces overproduction of the inducible enzymes iNOS and suppresses the release of the inflammatory factors TNF-α, IL-6 and NO.
BCN4899	Coniferaldehyde
1. Coniferaldehyde exerts anti-inflammatory properties by inducing heme oxygenase-1(HO-1), it inhibits LPS-induced apoptosis through the PKC α/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. 2. Coniferaldehyde can significantly inhibit the growth of viability of strains of Oenococcus oeni .
BCN4900	Sinapaldehyde
1. Sinapaldehyde has effects against 65 strains of Candida . 2. The reaction of sinapaldehyde and methylpyranoanthocyanin can obtain a new bluish pigment. 3. Sinapaldehyde inhibits prostaglandin synthetase in a dose-dependent way, it dose-dependently inhibits ethyl phenylpropiolate-induced edema of the rat ear, and can inhibit electrically induced contractions of the guinea pig ileum in a dose-dependent way.
BCN4922	Taxiphyllin
1. Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. 2. Taxiphyllin displays mild antibacterial activity against Staphylococcus aureus.

Inhibitors Bioactivity Products