Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5123 | Mayumbine |
| 1. Mayumbine (IC50 = 76 ± 3.5 nM) potently inhibit the in vitro binding of 3H-diazepam to the benzodiazepine sites within the rat GABAA receptor complex. | |
| BCN5142 | 6',7'-Dihydroxybergamottin |
| 6',7'-Dihydroxybergamottin(DHB), a well-known inhibitor of CYP3A4, the inhibition of CYP3A4 activity by DHB includes the inhibition of POR activity, DHB can inhibit nifedipine oxidation in a concentration-dependent manner. | |
| BCN5150 | Xanthatin |
| Xanthatin is a novel potent inhibitor of VEGFR2 signaling, has significant antitumor activity against a variety of cancer cells through cell cycle arrest and apoptosis induction, it can inhibit angiogenesis and tumor growth in breast cancer cells. Xanthatin has bactericidal and fungicidal activity, including against Colletotrichum gloesporoides, Trichothecium roseum, Bacillus cereus and Staphylococcus aureus. | |
| BCN5162 | Xanthohumol D |
| 1. Xanthohumol and xanthohumol D are potent inducers of quinone reductase, suggests that they could be used as chemoprevention agents. | |
| BCN5179 | 11beta-Hydroxycedrelone |
| 1. 11β-Hydroxycedrelone has cytotoxic activity, it exhibits moderate inhibitory activity against HL-60 cell line with the IC50 values of 8.9 uM. | |
