Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5056 | Guaijaverin |
| Guaijaverin is a urease inhibitor, it (IC(50)=0.18 microM) shows an inhibitory effect on rat lens aldose reductase. Guaijaverin has antioxidant, hypoglycemic activity and inhibitory capacity against free fatty acid release.It demonstrates high potential antiplaque agent by inhibiting the growth of the Strep. Mutans. | |
| BCN5060 | 9-Hydroxy-alpha-lapachone |
| 1. 9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori , it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 microM. 2. 9-Hydroxy-alpha-lapachone exhibits potent inhibitory effects on lipopolysaccharide- induced NO synthesis in RAW 264.7 cells, with IC50 values of 4.64 microM, suggests that it may have anti-inflammatory activity. | |
| BCN5061 | Serratenediol |
| 1. Serratenediol has significant and dose-dependent growth inhibitory effects on HL-60 cells via regulating the ratio of Bax/Bcl-xL. 2. Serratenediol can promote the proliferation rate,alkaline phosphate(ALP) activity and some osteogenic gene expression of osteoblasts. 3. Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects being stronger than that of a representative control, oleanolic acid. | |
| BCN5101 | Celaphanol A |
| 1. Celaphanol A shows moderate inhibition in both NF-κB activation and nitric oxide production, suggests that it is a possible inhibitor of the NF-kappaB pathway and has antiinflammatory activity. | |
| BCN5105 | Monomethyl kolavate |
| 1. Monomethyl kolavate is a power Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) inhibitor, with an IC50 value of 12uM. | |
