Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4587 | Derrone |
| 1. Derrone may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens. 2. Derrone is a novel Aurora kinase inhibitor, it can significantly inhibit the formation and growth of MCF7 tumor spheroids. | |
| BCN4588 | Broussonin C |
| 1. Broussonin C and broussin are antifungal compounds. 2. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase. | |
| BCN4604 | N-Feruloyloctopamine |
| BCN4607 | Akuammigine |
| 1. Akuammidine shows a preference for mu-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 microM at mu-, delta- and kappa-opioid binding sites, respectively; the agonist actions of akuammidine in the mouse-isolated vas deferens were antagonised by naloxone and the mu-opioid receptor selective antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) confirming an action at mu-opioid receptors. 2. Akuammigine competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors, yielding pA2 values of 4.68. 3. Akuammigine has in vitro antimalarial activity. | |
| BCN4610 | Cyclomorusin |
| 1. Cyclomorusin , neoCyclomorusin and kuwanon C inhibited cholinesterase enzyme in a dose-dependent manner with K(i) values ranging between 3.1 and 37.5 uM and between 1.7 and 19.1 uM against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes, respectively. 2. Cyclomorusin exhibits competitive inhibition toward monophenolase activity of mushroom tyrosinase, the IC50 value of 0.092 microM. 3. Cyclomorusin evokes the stimulation of superoxide anion generation in fMLP-stimulated rat neutrophils. | |
