Broussonin C

CAS# 76045-49-3

Broussonin C

Catalog No. BCN4588----Order now to get a substantial discount!

Product Name & Size Price Stock
Broussonin C: 5mg $799 In Stock
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Quality Control of Broussonin C

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Chemical structure

Broussonin C

3D structure

Chemical Properties of Broussonin C

Cas No. 76045-49-3 SDF Download SDF
PubChem ID 442289 Appearance Powder
Formula C20H24O3 M.Wt 312.41
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-[3-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]propyl]benzene-1,3-diol
SMILES CC(=CCC1=C(C=CC(=C1)CCCC2=C(C=C(C=C2)O)O)O)C
Standard InChIKey CMOZGCJOTGLPKO-UHFFFAOYSA-N
Standard InChI InChI=1S/C20H24O3/c1-14(2)6-8-17-12-15(7-11-19(17)22)4-3-5-16-9-10-18(21)13-20(16)23/h6-7,9-13,21-23H,3-5,8H2,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Broussonin C

The branch of Broussonetia papyrifera

Biological Activity of Broussonin C

Description1. Broussonin C and broussin are antifungal compounds. 2. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase.
TargetsTyrosinase | Antifection

Broussonin C Dilution Calculator

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Broussonin C Molarity Calculator

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Preparing Stock Solutions of Broussonin C

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2009 mL 16.0046 mL 32.0092 mL 64.0184 mL 80.023 mL
5 mM 0.6402 mL 3.2009 mL 6.4018 mL 12.8037 mL 16.0046 mL
10 mM 0.3201 mL 1.6005 mL 3.2009 mL 6.4018 mL 8.0023 mL
50 mM 0.064 mL 0.3201 mL 0.6402 mL 1.2804 mL 1.6005 mL
100 mM 0.032 mL 0.16 mL 0.3201 mL 0.6402 mL 0.8002 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Broussonin C

Tyrosinase inhibitory effects of 1,3-diphenylpropanes from Broussonetia kazinoki.[Pubmed:19046886]

Bioorg Med Chem. 2009 Jan 1;17(1):35-41.

Six 1,3-diphenylpropanes exhibiting inhibitory activities against both the monophenolase and diphenolase actions of tyrosinase were isolated from the methanol (95%) extract of Broussonetia kazinoki. These compounds, 1-6, were identified as kazinol C (1), D (2), F (3), Broussonin C (4), kazinol S (5) and kazinol T (6). The latter two species (5 and 6) emerged to be new 1,3-diphenylpropanes which we fully spectroscopically characterized. The IC(50) values of compounds (1, 3-5) for monophenolase inhibition were determined to range between 0.43 and 17.9 microM. Compounds 1 and 3-5 also inhibited diphenolase significantly with IC(50) values of 22.8, 1.7, 0.57, and 26.9 microM, respectively. All four active tyrosinase inhibitors (1, 3-5) were competitive inhibitors. Interestigly they all mainfested simple reversible slow-binding inhibition against diphenolase. The most potent inhibitor, compound 4 diplayed the following kinetic parameters k(3)=0.0993 microM(-1)min(-1), k(4)=0.0048 min(-1), and K(i)(app)=0.0485 microM.

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