Products with Inhibitors bioactivity

Cat.No. Product Name
BCN4414 Clausine Z
1. Clausine Z exhibits inhibitory activity against cyclin-dependent kinase 5 (CDK5) and shows protective effects on cerebellar granule neurons in vitro.
BCN4417 Dihydrotanshinone I
Dihydrotanshinone I is a potent inhibitor of the HuR:RNA interaction, it exhibits strong inhibition towards human liver microsome (HLM)-catalyzed propofol glucuronidation, and UDP-glucuronosyltransferase (UGT) 1A7. Dihydrotanshinone I has antibacterial, anti-cancer, anti-angiogenic, and cytotoxic activities, it induces caspase and ROS dependent apoptosis and autophagy.
BCN4427 Alismol
1. Alismol acts primarily on nerve terminals and inhibits their responses to electrical stimulation by interfering with NAd release. 2. Alismol inhibits mainly Ca2+ influx through a voltage-dependent Ca2+ channel. 3. Alismol holds great promise for use in chemopreventive and chemotherapeutic strategies. 4. Alismol has antihypertensive action. 5. Alismol decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks. 6. Alismol has inhibitory effect to MMP3 expression and nitric oxide produced in microglial cells.
BCN4432 Kongensin A
1. Kongensin A is an effective heat shock protein 90 (HSP90) inhibitor that has potential anti-necroptosis and anti-inflammation applications.
BCN4442 Salicyl alcohol
Benzyl and salicyl alcohol, the local anesthetics, are effective inhibitors of lymphocyte-mediated cytolysis (LMC) in vitro.

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