Products with Inhibitors Bioactivity

Explore BioCrick products associated with Inhibitors biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN4133	Grandifloroside
1. Grandifloroside shows good antioxidative and potent anti-inflammatory activities, it also exhibits potent inhibitory activity against TNF-α and 5α-reductase, suggests that it might be developed as a source of potent anti-oxidative and anti-inflammatory agents and therapeutic agent for benign prostatic hypertrophy (BPH).
BCN4138	alpha-Mangostin
Alpha-Mangostin has neuroprotective, anti-cancer, antifungal, neuroprotective, renoprotective, antioxidant and anti-inflammatory activities. Alpha-Mangostin exhibits peripheral and central antinociception through modulation of opioid and vanilloid receptors, the glutamatergic system, and the larginine/NO/cGMP/PKC/K(+)-ATP pathways; it suppresses phorbol 12-myristate 13-acetate-induced MMP-2/MMP-9 expressions via alphavbeta3 integrin/FAK/ERK and NF-kappaB signaling pathway in human lung adenocarcinoma A549 cells. Alpha-Mangostin is also a novel competitive histamine H1 receptor antagonist in smooth muscle cells.
BCN4145	Deoxycalyciphylline B
1. Deoxycalyciphylline B exhibits hepatic toxicity. 2. Deoxycalyciphylline B and Methyl homosecodaphniphyllate show different inhibitory effects on thephenoloxidase (PO) of Spodoptera exigua (Hbner) and the inhibitor concentrations leading to 50% (IC50) activity lost are estimated to be 2.439 mmol·L-1 for deoxycalyciphyllineB and 0.879mmol·L-1 for methyl homosecodaphniphyllate,respectively.
BCN4151	epsilon-Viniferin
1. Epsilon-viniferin shows a human cytochrome P450 enzymes inhition activity. 2. Epsilon-Viniferin is a bacteriostatic stilbenoid as it antagonized the bactericidal activity of vancomycin. 3. Epsilon-viniferin and epsilon-viniferin pentaacetate slightly reduce cell proliferation but might protect from cell degenerescence. 4. Epsilon-viniferin exhibits good antioxidant capacity in the DMSO/O(-)(2) polar system (IC50= 0.14 mM). 5. (-)-Trans-epsilon-viniferin is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity, it may be of value as a structural template for the design and development of new antidepressant drugs.
BCN4152	alpha-Viniferin
Alpha-viniferin is a prostaglandin H2 synthase inhibitor, which has anti-inflammatory, anti-oxidant, anti-arthritis, and anti-tumor activities. Alpha-Viniferin inhibits AChE activity is specific, reversible and noncompetitive, in a dose-dependent manner, and the IC50 values of alpha-Viniferin were 2.0 microM. Alpha-Viniferin exhibits a dose-dependent inhibition on cyclooxygenase activity, where 50% of inhibition (IC50) was shown at a final concentration of about 7 microM, it down-regulates STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages.

Inhibitors Bioactivity Products