Products with Inhibitors bioactivity

Cat.No. Product Name
BCN3825 2,5-Dihydroxyacetophenone
2,5-Dihydroxyacetophenone is an uncompetitive inhibitor of murine tyrosinase (K(I) 0.28mm), it strongly inhibits both melanogenesis and cellular tyrosinase activity, it possesses anti-inflammatoryanti-anxiety, and neuroprotective qualities. 2,5-Dihydroxyacetophenone treatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPKs, it also can potentiate the pro-apoptotic and anti-proliferative effects of bortezomib in U266 cells.
BCN3826 Luteolin-3-O-beta-D-glucuronide
1. Luteolin 3'-O-beta-D-glucuronide is active in the inhibition of nitrite production in macrophages.
BCN3830 Incensole acetate
Incensole acetate is a novel anti-inflammatory compound that inhibits NF-κB activation. Incensole acetate has protective effects on cerebral ischemic injury, it can reduce depressive-like behavior and modulate hippocampal BDNF and CRF expression of submissive animals.
BCN3837 alpha-Asarone
1. Alpha-Asarone shows insecticidal activity.
BCN3844 6-Demethoxytangeretin
1. 6-Demethoxytangeretin has anti-inflammatory activity, it also can suppress production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase and mitogen-activated protein kinase pathways. 2. 6-Demethoxytangeretin can suppress the interleukin 1 (IL-1) induced production of proMMP-9/progelatinase B in rabbit synovial cells in a dose dependent manner (<64 microM).

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