Products with
Inhibitors bioactivity
Cat.No.
|
Product Name
|
BCN3961 |
8-Lavandulylkaempferol
|
1. 8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase and acetylcholinesterase, respectively.
2. 8-Lavandulylkaempferol shows inhibitory activities against aldose reductase, with the the IC50 of 0.79 microM. |
BCN3972 |
Guajadial B
|
1. Guajadial B shows cytotoxicities against five human cancer cell lines, it is the most effective having an IC50 value of 150 nM toward A549 cells.
2. Guajadial B acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage. |
BCN3985 |
Magnolianin
|
1. Magnolianin can inhibit strongly (IC50 = 0.45 uM) 5-HETE formation by die cytosol of guinea pig polymorphonuclear leukocytes. |
BCN4004 |
Moracin O
|
1. Moracin O and moracin P exhibit potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia.
2. Moracin O shows significant neuroprotective activity against glutamate-induced cell death in SK-N-SH cells.
3. Moracin O demonstrates a remarkable inhibition of the acetic acid-induced pain.
4. Moracin O has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 uM. |
BCN4012 |
Cyclo(L-Ala-L-Pro)
|
Cyclo(L-Ala-L-Pro) and cyclo(L-Val-L-Pro) inhibit aflatoxin production of Aspergillus parasiticus and Aspergillus flavus in liquid medium at concentrations of several hundred uM without affecting fungal growth. |