Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2880 | Carboxyatractyloside |
| 1. Carboxyatractyloside induces the inhibitory effect of tamoxifen on nonspecific membrane permeability. 2. Carboxyatractyloside can induce permeability transition, and that ageing induced mitochondrial DNA disruption and release of cytochrome c. 3. Carboxyatractyloside poisoning causes multiple organ dysfunction and can be fatal, the signs of a poor prognosis including coagulation abnormalities, hyponatraemia, marked hypoglycaemia, icterus and hepatic and renal failure, without antidote. | |
| BCN2891 | Sophoflavescenol |
| 1. Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. 2. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity without severe side effects. 3. Sophoflavescenol exerts notable anti-inflammatory activity by inhibiting nitric oxide generation and tert-butylhydroperoxide-induced ROS generation rather than inhibiting nuclear factor kappa B activation in RAW 264.7 cells. | |
| BCN2910 | 6,7,4'-Trihydroxyisoflavone |
| 1. 6,7,4'-Trihydroxyisoflavone has antioxidant activity. 2. 6,7,4'-Trihydroxyisoflavone, is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1. 3. 6,7,4'-trihydroxyisoflavone, suppresses adipogenesis in 3T3-L1 preadipocytes via ATP-competitive inhibition of PI3K. 4. 6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2. | |
| BCN2916 | Acetovanillone |
| Acetovanillone is the NADPH oxidase inhibitor, induces oxidative stress. | |
| BCN2929 | Licoisoflavone A |
| 1. Licoisoflavone A is a potential MRP inhibitor. 2. Licoisoflavone A and licoisoflavone B show inhibitory effects on copper-induced protein oxidative modification of mice brain homogenate in vitro. | |
