Products with
Inhibitors bioactivity
Cat.No.
|
Product Name
|
BCN3177 |
Isomahanine
|
1. Isomahanine and mahanine show antibacterial activity towards Flavobacterium columnare and Streptococcus iniae which caused columnaris disease and streptococcosis respectively; isomahanine has the strongest activity against F. columnare (isolate ALM-00-173) and S. iniae (isolate LA94-426) based on 24-h 50% inhibition concentration (IC50) and minimum inhibition concentration (MIC).
2. Isomahanine is a potent inhibitor of sEH , with IC50 values of 22.565±651.7. |
BCN3178 |
Murrayanol
|
1. Murrayanol has antioxidant activity.
2. Murrayanol shows an IC50 of 109 μg/mL against hPGHS-1 and an IC50 of 218 μg/mL against hPGHS-2 in antiinflammatory assays. |
BCN3185 |
Schisanlactone A
|
1. Schisanlactone A shows cytotoxicity against KB (a human epidermal carcinoma) cells with the IC50 value of 63.3 uM.
2. Schisanlactone A is a dimerization inhibitor, with an IC50 value of 5.0 microg/mL.
3. Schisanlactone A shows appreciable inhibitory activity against HIV-1 protease with the IC50 value of 20 microM. |
BCN3192 |
Isobavachromene
|
1. Isobavachromene has antifungal activity.
2. Isobavachromene is an inhibitor of NADH-Ubiquinone oxidoreductase and ornithine decarboxylase. |
BCN3194 |
Neobavaisoflavone
|
Neobavaisoflavone, exhibits inhibitory activity against DNA polymerase and platelet aggregation, it also has striking anti-inflammatory and anti-cancer effects, Neobavaisoflavone can significantly inhibit the production of reactive oxygen species (ROS), reactive nitrogen species (RNS) and cytokines: IL-1β, IL-6, IL-12p40, IL-12p70, TNF-α in LPS+IFN-γ- or PMA- stimulated RAW264.7 macrophages. |