Products with Inhibitors Bioactivity

Explore BioCrick products associated with Inhibitors biological activity, including catalog numbers, product names and available bioactivity information.

Inhibitors Bioactivity Products

Cat. No. Product Name
BCN3263 Chebulinic acid
Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity; it also is a natural inhibitor of vascular endothelial growth factor-A mediated angiogenesis. Chebulinic acid has hypotensive, antioxidant, anti-HIV, and anti-ulcer activities. Chebulinic acid has inhibitory effect on erythroid differentiation likely through changing transcriptional activation of differentiation relative genes, it or other tannins might influence the efficiency of some anti-tumor drugs-induced differentiation or the hematopoiesis processes.
BCN3288 Chlorophorin
1. Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. 2. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of 2.5 ± 0.408 uM. 3. Chlorophorin can reduce tyrosinase activity and inhibit α-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells.
BCN3289 Moracin P
1. Moracin P shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells. 2. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia. 3. Moracin P might protect neuronal cell death against the oxidative stress induced by oxygen-glucose deprivation(OGD), can enhance cell viability in dose-dependent manner against OGD-induced cell death in neuroblastoma SH-SY5Y cells.
BCN3290 Albanin A
1. Albanin A shows mushroom tyrosinase inhibitory activity, the IC50 value is 463 uM. 2. In melanin formation inhibition on B16 melanoma cells, the IC50 of albanin A is 40.1 uM.
BCN3292 Moracin M
1. Moracin M is a phytoalexin. 2. Moracin M inhibits PDE4D2, PDE4B2, PDE5A1, and PDE9A2 with the IC(50) values of 2.9, 4.5, >40, and >100 μM, respectively.

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