Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3263 | Chebulinic acid |
| Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity; it also is a natural inhibitor of vascular endothelial growth factor-A mediated angiogenesis. Chebulinic acid has hypotensive, antioxidant, anti-HIV, and anti-ulcer activities. Chebulinic acid has inhibitory effect on erythroid differentiation likely through changing transcriptional activation of differentiation relative genes, it or other tannins might influence the efficiency of some anti-tumor drugs-induced differentiation or the hematopoiesis processes. | |
| BCN3288 | Chlorophorin |
| 1. Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. 2. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of 2.5 ± 0.408 uM. 3. Chlorophorin can reduce tyrosinase activity and inhibit α-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells. | |
| BCN3289 | Moracin P |
| 1. Moracin P shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells. 2. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia. 3. Moracin P might protect neuronal cell death against the oxidative stress induced by oxygen-glucose deprivation(OGD), can enhance cell viability in dose-dependent manner against OGD-induced cell death in neuroblastoma SH-SY5Y cells. | |
| BCN3290 | Albanin A |
| 1. Albanin A shows mushroom tyrosinase inhibitory activity, the IC50 value is 463 uM. 2. In melanin formation inhibition on B16 melanoma cells, the IC50 of albanin A is 40.1 uM. | |
| BCN3292 | Moracin M |
| 1. Moracin M is a phytoalexin. 2. Moracin M inhibits PDE4D2, PDE4B2, PDE5A1, and PDE9A2 with the IC(50) values of 2.9, 4.5, >40, and >100 μM, respectively. | |
