Products with Pro-osteoblastogenesis bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5962 | Astragaloside II |
| Astragaloside II is a potent autophagy inhibitor and multidrug resistance (MDR) reversal agent, which restores chemosensitivity of anticancer agent cisplatin and enhances tumor cell death. It has immunomodulating activity, can trigger T cell activation through regulation of CD45 protein tyrosine phosphatase activity, it induces osteogenic activities of osteoblasts through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways. | |
| BCN6131 | 26-Nor-8-oxo-alpha-onocerin |
| 1. 26-Nor-8-oxo-alpha-onocerin can promote the osteoblast proliferation rate, the effect is time-dependent,concentration-dependent and differentiation state-dependent. | |
| BCN6204 | Oplodiol |
| 1. Oplodiol exhibits noteworthy anti-plasmodial activity against Plasmodium falciparum strains. 2. Oplodiol has a stimulative effect on significantly proliferation and differentiation of culture osteoblasts. 3. Oplodiol shows moderate cytotoxic effects on the human lung adenocarcinoma A549 with IC50 values at 25.5 ug/mL. | |
| BCN6280 | Monotropein |
| Monotropein has anti-antiosteoporosis and anti-inflammatory activities, it exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes and can increase osteoblastic bone formation and prevent bone loss in ovariectomized mice. | |
| BCN6329 | Emodin-8-beta-D-glucoside |
| Emodin-8-beta-D-glucoside functions to protect from focal cerebral injury induced by ischemia and reperfusion. It directly stimulates cell proliferation and differentiation of osteoblasts. | |
