Products with Pro-osteoblastogenesis bioactivity

Cat.No. Product Name
BCN3091 2-Hydroxy-1-methoxyanthraquinone
1. 2-Hydroxy-1-methoxy- anthraquinone can promote osteoblast proliferation, and can inhibit osteoclast TRAP activity and bone resorption, suggests that it has antiosteoporotic activity.
BCN3311 8-Prenylkaempferol
1. 8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction. 2. 8-Prenylkaempferol induces differentiation/maturation of MC3T3-E1 osteoblasts by BMP-2/p38/Runx2 pathways , might be a promising agent for inducing osteogenesis. 3. 8-Prenylkaempferol might be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated transcriptional activation of NF-κB and IRF-3 and in part by interfering with IκB degradation which subsequently decreases NF-κB translocation.
BCN3444 Kobophenol A
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell death. Kobophenol A inhibits AChE activity in a dose-dependent manner, and the IC50 value is 115.8mM. Kobophenol A has protective effect against nitrosative/oxidative or mitochondrial damages resulted in the inhibition of the ROS, intracellular calcium ion level, and mitochondrial transmembrane potential changes on SH-SY5Y cells.
BCN4543 Bullatantriol
1. Bullatantriol has a stimulative effect on significantly proliferation and differentiation of culture osteoblasts. 2. Bullatantriol may have weak antibacterial activities.
BCN4805 6,8-Diprenylgenistein
1. 6,8-Diprenylgenistein has antimicrobial activity . 2. 6,8-Diprenylgenistein has anti-bacteria activity against Gram-negative and Gram-positive bacteria.

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