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Angelica biserrata

Angelica biserrata

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Natural products/compounds from  Angelica biserrata

  1. Cat.No. Product Name CAS Number COA
  2. BCN8246 Angenomalin18199-64-9 Instructions
  3. BCN5065 Falcarindiol225110-25-8 Instructions
  4. BCN2652 Columbianetin acetate23180-65-6 Instructions
  5. BCN5205 Xanthotoxin298-81-7 Instructions
  6. BCN2331 (+)-columbianetin3804-70-4 Instructions
  7. BCN9028 Byakangelicin482-25-7 Instructions
  8. BCN5568 Isopimpinellin482-27-9 Instructions
  9. BCN5897 Isoimperatorin482-45-1 Instructions
  10. BCN5581 Osthol484-12-8 Instructions
  11. BCN5582 Bergapten484-20-8 Instructions
  12. BCN3617 Ammijin495-30-7 Instructions
  13. BCN2378 Nodakenin495-31-8 Instructions
  14. BCN5604 Nodakenetin495-32-9 Instructions
  15. BCN1275 Columbianadin5058-13-9 Instructions
  16. BCN4219 Psoralen66-97-7 Instructions
  17. BCN8037 Angelol B83156-04-1 Instructions
  18. BCN6309 Coumarin91-64-5 Instructions
  19. BCN4470 Scopoletin92-61-5 Instructions
  20. BCN4477 Umbelliferone93-35-6 Instructions

References

Analgesic effect of coumarins from Radix angelicae pubescentis is mediated by inflammatory factors and TRPV1 in a spared nerve injury model of neuropathic pain.[Pubmed: 27915078]


Coumarins from Radix angelicae pubescentis (CRAP) are a major active component that are isolated from dried roots of Angelica biserrata Yuan et Shan, which has been used clinically to cure headaches for a long period of time, and it is an effective treatment for pain. The aim of the present study was to investigate the analgesic effect of CRAP on a spared nerve injury (SNI) model of neuropathy.


Rapid Authentication of the Herbal Medicine Plant Species Aralia continentalis Kitag. and Angelica biserrata C.Q. Yuan and R.H. Shan Using ITS2 Sequences and Multiplex-SCAR Markers.[Pubmed: 26938512]


Accurate identification of the plant species that are present in herbal medicines is important for quality control. Although the dried roots of Aralia continentalis (Araliae Continentalis Radix) and Angelica biserrata (Angelicae Pubescentis Radix) are used in the same traditional medicine, namely Dok-Hwal in Korean and Du-Huo in Chinese, the medicines are described differently in the national pharmacopeia. Further confusion arises from the distribution of dried Levisticum officinale and Heracleum moellendorffii roots as the same medicine. Medicinal ingredients from all four plants are morphologically similar, and discrimination is difficult using conventional methods. Molecular identification methods offer rapidity and accuracy. The internal transcribed spacer 2 (ITS2) region of the nuclear ribosomal RNA gene (rDNA) was sequenced in all four plant species, and the sequences were used to design species-specific primers. Primers for each species were then combined to allow sample analysis in a single PCR reaction. Commercial herbal medicine samples were obtained from Korea and China and analyzed using the multiplex assay. The assay successfully identified authentic medicines and also identified inauthentic or adulterated samples. The multiplex assay will be a useful tool for identification of authentic Araliae Continentalis Radix and/or Angelicae Pubescentis Radix preparations in Korea and China.