Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 5745 - 5752 of 9359 hot products
| Catalog No. | Product Name |
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| BCN3894 | Gliotoxin |
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1. Gliotoxin targets nuclear NOTCH2 in human solid tumor derived cell lines in vitro and inhibits melanoma growth in xenograft mouse model.
2. Gliotoxin exhibits very strong anti-tuberculosis activity towards Mycobacterium tuberculosis with the the prominent MIC50 value of <0.03 uM. 3. Gliotoxin displays significant selective cytotoxicities against K562, A549 and Huh-7 cell lines with the IC50 values of 0.191, 0.015 and 95.4 uM, respectively. 4. Gliotoxin suppresses macrophage immune function by subverting phosphatidylinositol 3,4,5-trisphosphate homeostasis. 5. Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signaling pathway. |
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| BCN3895 | beta-Thujaplicin |
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1. Hinokitiol can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent.
2. Hinokitiol has antibacterial effect , it can inhibit all Staphylococcus aureus isolates with MICs of 1.56-3.13 mg/L. 3. Hinokitiol has antifungal activity against 51 Malassezia pachydermatis strains, it is an inexpensive and safe treatment with anti-inflammatory and deodorant effects that can be recommended as an effective remedy for canine otitis externa. 4. beta-thujaplicin (Hinokitiol) has ability to extract mitochondrial Mg++ and the prevention of the effects of beta-thujaplicin by an excess of Mg++ in the medium, suggests a common mode of action of beta-thujaplicin as a lipophilic chelator of Mg++ and other divalent cations. |
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| BCN3898 | Cleomiscosin B |
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1. Cleomiscosins A, B and C exhibit liver-protective properties.
2. Cleomiscosin B shows the potent anti-HIV-1 activity in vitro and also has protective effects on MT4 cells infected by HIV-1(IIIB). |
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| BCN3900 | Moschamine |
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1. Moschamine may suppress cAMP formation via binding to 5-HT1 receptors in the cells.
2. Moschamine is a very potent compound that is able to inhibit COX-I by 58% and COX-II by 54%, at the concentration of 0.1 μmol L⁻1. 3. Moschamine exerts antitumour effects on HeLa, MCF7 and A431 cells. |
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| BCN3901 | cis-Moschamine |
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1. cis-Moschamine exerts antitumour effects on HeLa, MCF7 and A431 cells.
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| BCN3902 | Gomisin H |
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Gomisin H is a natural product from Schizandra chinensis.
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| BCN3903 | 12-Oleanene-3,6-diol |
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12-Oleanene-3,6-diol has antitumor activity, it can induce apoptosis and has inhibition effect on the proliferation in RKO cell line.
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| BCN3904 | Daturaolone |
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1. Daturaolone has potency in reducing the harmful effects or in maintaining the normal hepatic physiological mechanisms in both acute and chronic hepato-toxic induced liver damage in rats.
2. Daturaolone possesses in vivo anti-inflammatory and antinociceptive potentials, which are supported in silico by an interaction with COXs receptors. |
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