Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6661 | 4-DAMP |
| Antagonist at the M3 cholinergic receptor. [3H]-4-DAMP selectively labels M1 and M3 receptors. | |
| BCC6662 | Dioctanoylglycol |
| Specific inhibitor of diacylglycerol kinase. | |
| BCC6664 | 1,3-Dipropyl-8-phenylxanthine |
| Selective A1 adenosine antagonist. | |
| BCC6666 | (-)-U-50488 hydrochloride |
| More active enantiomer of (±)-U-50488. (+)-U-50488 hydrochloride also available. | |
| BCC6673 | Dantrolene, sodium salt |
| Inhibits release of Ca2+ from sarcoplasmic reticulum via inhibition of ryanodine receptor (RYR) channels. Displays selectivity for RYR1 and RYR3 over RYR2. Protective against the effects of a variety of conditions and agents, including excitatory amino acids. Skeletal muscle relaxant and neuroprotectant. | |
| BCC6675 | SKF 91488 dihydrochloride |
| Homolog of dimaprit; strong inhibitor of histamine N-methyltransferase. Exhibits no histamine agonist activity. | |
| BCC6676 | GBR 12783 dihydrochloride |
| A very potent and selective inhibitor of dopamine uptake (IC50 for inhibition of [3H]-dopamine uptake in rat striatal synaptosomes is 1.8 nM). | |
| BCC6677 | EBPC |
| Potent aldose reductase inhibitor. Improves the cytotoxicity of anticancer reagents such as cisplatin and doxorubicin in HeLa cervical carcinoma cells through an increase in ERK activity. | |
