Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6742 | trans-Triprolidine hydrochloride |
| Potent H1 receptor antagonist. | |
| BCC6743 | 3-AQC |
| A competitive 5-HT3 antagonist, almost 100 times more potent than tropisetron, but with widely differing activity in various tissues. | |
| BCC6744 | Amthamine dihydrobromide |
| Highly selective H2 agonist, slightly more potent than histamine itself. Only a weak antagonist at H3 and has no activity at H1 receptors. Induces vasodilation of cerebral arteries and decreases myogenic tone in vitro. | |
| BCC6745 | PK 11195 |
| Possesses high affinity for the peripheral benzodiazepine receptor (PBR, TSPO) without binding to other known neurotransmitter receptors. Also inhibits the human constitutive androstane receptor (hCAR). | |
| BCC6746 | L-Canavanine sulfate |
| NO synthase inhibitor. | |
| BCC6747 | (+)-AJ 76 hydrochloride |
| Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively). | |
| BCC6748 | 2-Phenylmelatonin |
| Highly potent melatonin agonist; displays higher affinity and greater potency than melatonin itself. The EC50 values for G protein activation in MT1 and MT2-transfected cells are 65 and 58 pM respectively. | |
| BCC6749 | iso-PPADS tetrasodium salt |
| P2X-purinoceptor antagonist (pKi = 6.5) with similar activity to PPADS. | |
