Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6781 | Clobenpropit dihydrobromide |
| An extremely potent histamine H3 antagonist/inverse agonist (pA2=9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM. Also available as part of the Histamine H3 Receptor. | |
| BCC6786 | Bifemelane hydrochloride |
| Antidepressant MAO inhibitor. Reverses catalepsy induced by tetrabenazine in mice and increases locomotor activity in MPTP-treated marmosets. | |
| BCC6787 | GBLD 345 |
| A high affinity benzodiazepine agonist (IC50 against diazepam = 1 nM). | |
| BCC6790 | (+)-UH 232 maleate |
| D2 antagonist (Ki = 72.7 nM in a ligand binding assay; apparent KB = 14.5 nM in a cAMP accumulation assay); displays preferential activity at central dopamine autoreceptors. Stimulates a marked acceleration of dopamine synthesis and turnover. Produces locomotor stimulation. Exhibits little or no activity at central noradrenalin and 5-HT receptors. Also D3 partial agonist. | |
| BCC6791 | (S)-Methylisothiourea sulfate |
| Highly selective, potent competitive inhibitor of iNOS. | |
| BCC6793 | Iodophenpropit dihydrobromide |
| Selective H3 antagonist with high affinity (KD = 0.3 nM). Also available as part of the Histamine H3 Receptor. | |
| BCC6795 | Aminoguanidine hydrochloride |
| Irreversible inhibitor of iNOS that displays some selectivity over eNOS and nNOS. Exhibits antioxidant and radioprotective effects in vivo. | |
| BCC6800 | 8-Hydroxy-PIPAT oxalate |
| High affinity 5-HT1A receptor agonist (Kd = 0.38 nM). 7-Hydroxy-PIPAT maleate also available. | |
