Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6801 | MSOP |
| Selective group III metabotropic glutamate receptor antagonist. Displays an apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord compared to > 700 μM for the (1S,3S)-ACPD-sensitive presynaptic mGlu in the same system. Has no activity on postsynaptic mGlu receptors or on ionotropic glutamate receptors on neonatal rat motoneurons. Also available as part of the Group III mGlu Receptor Tocriset™. | |
| BCC6802 | (S)-3,5-DHPG |
| Selective group I mGlu receptor agonist. Also available as part of the Group I mGlu Receptor and Mixed mGlu Receptor. (RS)-3,5-DHPG also available. | |
| BCC6805 | (2R,3S)-Chlorpheg |
| A weakly active NMDA receptor antagonist. | |
| BCC6806 | ICI 204,448 hydrochloride |
| Peripherally acting κ agonist. | |
| BCC6808 | ICI 162,846 |
| A potent histamine H2 receptor antagonist. | |
| BCC6811 | DHBP dibromide |
| Blocks calcium release from sarcoplasmic reticulum by direct interaction with the ryanodine receptor. | |
| BCC6813 | Agmatine sulfate |
| Arginine metabolite that is synthesized within bovine brain and exhibits clonidine-displacing substance (CDS) activity. Putative endogenous ligand for the imidazoline binding site. | |
| BCC6814 | Oxotremorine sesquifumarate |
| Muscarinic agonist. | |
