Hot Natural Products & Bioactive Compounds

BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.

Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.

Hot Products from BioCrick

Showing 7257 - 7264 of 9359 hot products

BioCrick hot natural products and bioactive compounds
Catalog No. Product Name
BCN5790 Aurantiamide
1. Aurantiamide acetate may suppress the growth of malignant gliomas by blocking autophagic flux.
2. Aurantiamide acetate has an anti-neuroinflammatory effect on LPS stimulation through its inhibition of the NF-κB, JNK and p38 pathways.
3. Aurantiamide acetate inhibits cysteine proteinases, in particular, cathepsin L (3.4.22.15) and B (3.4.22.1) with IC50 of 12 microM and 49 microM, respectively .
4. Aurantiamide acetate is the main active substance of EECTD, which has significant anti-inflammatory and antinociceptive activities.
BCN5791 Suberosin
Suberosin exhibits anti-inflammatory, and anticoagulant activities, it also shows biting deterrent activity against Aedes aegypti, it may be useful for use as mosquito larvicidal agent. Suberosin inhibits PHA-induced PBMC proliferation, at least in part, through reduction of [Ca2+]i, ERK, NF-AT, and NF-kappaB activation, and early gene expression in PBMC including cyclins and cytokines, and arrest of cell cycle progression in the cells.
BCN5793 Dihydroresveratrol
Dihydroresveratrol has antiproliferative activity against human prostate cancer PC3 cell line in vitro, it can ameliorate acute pancreatitis-associated lung injury via an inhibitory modulation of pro-inflammatory response, which is associated with a suppression of the NF-κB signaling pathway.
BCN5794 Gomisin A
Gomisin A has anti-inflammatory, antihypertensive, neuroprotective, and anti-proliferation properties, it induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. Gomisin A inhibits COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation.
BCN5795 Confluentin
1. Confluentin has antimicrobial activity against the gram-positive bacteria.
2. Confluentin significantly inhibits compound 48/80-induced histamine release from rat peritoneal mast cells.
3. Confluentin shows weak cytotoxicity against four human tumor cell lines, HL-60, SMMC-7712, A-549, and MCF-7, in vitro.
BCN5796 Adenosine
Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond. Adenosine induces SphK1 activity in human and mouse sickle and normal erythrocytes in vitro, it can activate the neuroimmune system, alter neuronal function and neurotransmission,and contribute to symptoms of sickness and psychopathologies. Adenosine activates mast cells have been long implicated in allergic asthma and studies in rodent mast cells have assigned the A3 Adenosine receptor (A3R) a primary role in mediating Adenosine responses.
BCN5798 Meranzin hydrate
1. Meranzin hydrate produces a rapid effect mediated by AMPA receptors and involving BDNF modulation through the ERK1/2 pathway.
2. Chronic mild stress accelerates the absorption of Meranzin hydrate in rats following the oral administration of Chaihu-Shugan-San.
3. Meranzin hydrate can induce similar effect to Fructus Aurantii on intestinal motility and it was, at least in part, mediated by stimulation of H1 histamine receptors.
4. Meranzin hydrate exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.
BCN5800 Secoxyloganin
Secoxyloganin possesses hepato- protective, cytotoxic, and antibacterial activities,
it has the perfect protective effect on PRRSV infected cell and with the minimum protection concentration of 6. 25 Âμg/mL.