Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6899 | CP 93129 dihydrochloride |
| Potent and highly selective 5-HT1B agonist (Ki values are 8.1, 1100, 1500, 2900 and 7200 nM for 5-HT1B, 5-HT1D, 5-HT1A, 5-HT1c and 5-HT2, respectively). Reduces food intake and decreases body weight in rats. | |
| BCC6901 | 8-M-PDOT |
| Melatonin receptor agonist, 20-fold selective for the MT2 (vs MT1) subtype. At human recombinant MT1 and MT2 receptors, displays pKi values of 8.23 and 8.95 respectively. | |
| BCC6902 | ZM 241385 |
| Potent and highly selective A2A adenosine antagonist, with a pA2 of 9.02 for A2A receptors in guinea pig cardiac vasculature and fold selectivities of 1000, 91 and 500,000 over A1, A2B and A3 sites respectively. Active in vivo. | |
| BCC6904 | 1-EBIO |
| Activator of epithelial KCa channels, stimulates a large and sustained trans-epithelial Cl- secretory response across T84 monolayers. Induces hyperpolarization to the same magnitude as ACh in aortic value endothelial cells. Promotes embryonic stem cell (ESC) differentiation into cardiomyocytes. | |
| BCC6905 | N-Methyllidocaine iodide |
| Antiarrhythmic. Enhances the biosynthesis of phosphatidylinositol in hamster heart. | |
| BCC6906 | QX 222 |
| Sodium channel blocker. | |
| BCC6907 | NBQX disodium salt |
| Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo. More water soluble disodium salt of NBQX. Also available as part of the AMPA Receptor. | |
| BCC6908 | CNQX disodium salt |
| More water soluble disodium salt of the AMPA/kainate antagonist CNQX. Also available as part of the Kainate Receptor. | |
