Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6951 | Resiniferatoxin |
| Potent analog of capsaicin that is an agonist at vanilloid receptors (Ki = 43 pM). Like capsaicin, it acts as a selective modulator of primary afferent neurons. Also available as part of the Vanilloid TRPV1 Receptor. | |
| BCC6952 | Thapsigargin |
| Potent inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases. Causes ER stress; can be used to induce autophagy in mammalian cells. | |
| BCC6953 | SKF 96365 hydrochloride |
| Store-operated Ca2+ entry (SOCE) inhibitor that inhibits STIM1. Also blocks TRPC channels, voltage-gated Ca2+ channels and potassium channels. | |
| BCC6954 | Siguazodan |
| Phosphodiesterase inhibitor, selective for PDE3 (IC50 = 117 nM). | |
| BCC6955 | Neurokinin A (porcine) |
| Endogenous tachykinin peptide; more potent bronchoconstrictor than Substance P. | |
| BCC6956 | RR-src |
| Tyrosine kinase substrate peptide. | |
| BCC6957 | Substance P |
| Sensory neuropeptide and inflammatory mediator. Exerts excitatory effects on central and peripheral neurons, constricts bronchioles and is involved in pain transmission. | |
| BCC6959 | Neuropeptide Y 13-36 (porcine) |
| Neuropeptide Y2 receptor agonist. | |
