Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6824 | EIT hydrobromide |
| Potent, selective and reversible inhibitor of isoform II NO synthase (IC50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively). | |
| BCC6826 | Luzindole |
| Melatonin antagonist. | |
| BCC6829 | ODQ |
| A potent and selective inhibitor of NO-sensitive guanylyl cyclase. | |
| BCC6830 | Chlormethiazole hydrochloride |
| Sedative and anticonvulsant which is neuroprotective in a number of animal models. Prevents the degeneration of serotonergic nerve terminals induced by MDMA ('Ecstasy'). | |
| BCC6835 | (RS)-(±)-Sulpiride |
| Standard D2-like dopamine receptor antagonist. (S)-(-)-Sulpiride also available. | |
| BCC6836 | GR 135531 |
| Binds with high affinity to MT3 melatonin sites in hamster brain, and low affinity (and no efficacy) at MT1 and MT2 melatonin receptors and thus can be used to discriminate between the melatonin receptor subtypes. | |
| BCC6837 | S-Isopropylisothiourea hydrobromide |
| Potent inhibitor of NO synthase, with selectivity for the inducible form. | |
| BCC6839 | 5-Nonyloxytryptamine oxalate |
| 5-HT1B selective agonist, several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold). Mimics polysialic acid activity, stimulates neuritogenesis, myelination and Schwann cell migration in vitro. | |
