Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 7185 - 7192 of 9359 hot products
| Catalog No. | Product Name |
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| BCN5705 | 1,3,5-Trihydroxy-4-prenylxanthone |
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1. 1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM.
2. 1,3,5-Trihydroxy-4-prenylxanthone inhibits LPS-induced NF-κB and AP-1 activations by interfering with the posttranslational modification (phosphorylation and/or ubiquitinylation) of IRAK-1 in the cell membrane to impede TAK1-mediated activation of IKK and MAPKs signal transduction. 3. 1,3,5-Trihydroxy-4-prenylxanthone shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 56.3plusmn;0.4 and 46.0plusmn;0.3 M, respectively. |
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| BCN5708 | Apigenin 7-O-methylglucuronide |
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1. Apigenin 7-O-methylglucuronide did not affect GAG level or secretion, may potentially be used in osteogenesis imperfecta (OI) type I pharmacotherapy in patients with normal GAG content.
2. Apigenin 7-O-methylglucuronide which normalized collagen synthesis in OI cells may exert their effects through beta1-integrin-mediated signaling. |
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| BCN5709 | 1-Hydroxyrutaecarpine |
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1. 1-Hydroxyrutaecarpine exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 or HT-29 cell lines in vitro.
2. 1-Hydroxyrutaecarpine exhibits antiplatelet activity induced by AA and shows an IC50 value of ca.1-2 micrograms/ml. 3. 1-Hydroxyrutaecarpine displays moderate inhibitory activity on those enzymes(Cathepsins B, L and K) at the concentration of 125 ug/ml. |
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| BCN5710 | Lyclaninol |
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Standard reference
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| BCN5712 | Onitin |
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1. Onitin shows super-oxide and DPPH free radical scavenging effects.
2. Onitin exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. |
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| BCN5713 | Onitisin |
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1. Onitisin, onitinoside and onitin can inhibit the contraction of isolated guinea-pig ileum.
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| BCN5715 | Caboxine A |
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Standard reference
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| BCN5716 | Corylin |
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Corylin has a variety of pharmacological effects such as antioxidant, anti-proliferation, and anti-inflammatory properties, it may stimulate bone formation or have potential activity against osteoporosis. Corylin shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells.
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