15-Hydroxydehydroabietic acidCAS# 54113-95-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 54113-95-0 | SDF | Download SDF |
PubChem ID | 14487943 | Appearance | Powder |
Formula | C20H28O3 | M.Wt | 316.4 |
Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | (1R,4aS,10aR)-7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid | ||
SMILES | CC12CCCC(C1CCC3=C2C=CC(=C3)C(C)(C)O)(C)C(=O)O | ||
Standard InChIKey | ILQLITDRYFHAGM-NSISKUIASA-N | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | 1. 15-Hydroxydehydroabietic acid exhibits a promising alpha-glucosidase inhibitory activity, it also shows significant antibacterial activities. |
Targets | Antifection | P450 (e.g. CYP17) |
15-Hydroxydehydroabietic acid Dilution Calculator
15-Hydroxydehydroabietic acid Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 3.1606 mL | 15.8028 mL | 31.6056 mL | 63.2111 mL | 79.0139 mL |
5 mM | 0.6321 mL | 3.1606 mL | 6.3211 mL | 12.6422 mL | 15.8028 mL |
10 mM | 0.3161 mL | 1.5803 mL | 3.1606 mL | 6.3211 mL | 7.9014 mL |
50 mM | 0.0632 mL | 0.3161 mL | 0.6321 mL | 1.2642 mL | 1.5803 mL |
100 mM | 0.0316 mL | 0.158 mL | 0.3161 mL | 0.6321 mL | 0.7901 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Muscone
Catalog No.:BCN6275
CAS No.:541-91-3
- Isovaleramide
Catalog No.:BCC4668
CAS No.:541-46-8
- Decamethonium Bromide
Catalog No.:BCC4568
CAS No.:541-22-0
- L-Carnitine inner salt
Catalog No.:BCN1229
CAS No.:541-15-1
- 2-(1-Hydroxy-1-methylethyl)-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one
Catalog No.:BCN1422
CAS No.:54087-32-0
- Isoastilbin
Catalog No.:BCN5719
CAS No.:54081-48-0
- Palosuran
Catalog No.:BCC4311
CAS No.:540769-28-6
- Tofacitinib (CP-690550) Citrate
Catalog No.:BCC2189
CAS No.:540737-29-9
- Etonogestrel
Catalog No.:BCC5230
CAS No.:54048-10-1
- Albendazole Oxide
Catalog No.:BCC4757
CAS No.:54029-12-8
- Amifampridine
Catalog No.:BCC5185
CAS No.:54-96-6
- Pentylenetetrazole
Catalog No.:BCC7453
CAS No.:54-95-5
- 9-Benzylcarbazole-3-carboxaldehyde
Catalog No.:BCC8800
CAS No.:54117-37-2
- Apoptosis Inhibitor
Catalog No.:BCC1143
CAS No.:54135-60-3
- Neoisoastilbin
Catalog No.:BCN6532
CAS No.:54141-72-9
- Flecainide acetate
Catalog No.:BCC1578
CAS No.:54143-56-5
- Vicriviroc Malate
Catalog No.:BCC1230
CAS No.:541503-81-5
- Apilimod
Catalog No.:BCC5286
CAS No.:541550-19-0
- 1-Monopalmitin
Catalog No.:BCN7749
CAS No.:542-44-9
- Cimaterol
Catalog No.:BCC6647
CAS No.:54239-37-1
- 3-Benzoylpyridine
Catalog No.:BCC8623
CAS No.:5424-19-1
- Stachyose trihydrate
Catalog No.:BCN8361
CAS No.:54261-98-2
- (+)-Fluprostenol
Catalog No.:BCC7947
CAS No.:54276-17-4
- 2',4'-Dihydroxy-3',6'-dimethoxydihydrochalcone
Catalog No.:BCN1421
CAS No.:54299-52-4
Oxidized resin acids in aerosol derived from rosin core solder.[Pubmed:9866169]
Am Ind Hyg Assoc J. 1998 Dec;59(12):889-94.
Exposure to rosin during a variety of uses has been associated with dermal and pulmonary sensitization. Oxidized resin acids are present in many rosin products, and have been regarded as the main sensitizing rosin compounds in cases of dermal sensitization. This research describes oxidized resin acids identified in aerosol produced during soldering with rosin core solder. Oxidized resin acids found were 7-oxodehydroabietic acid, 15-Hydroxydehydroabietic acid, and 7-hydroxydehydroabietic acid. The presence of oxidized compounds known to be dermal sensitizers in aerosol from rosin flux soldering supports the hypothesis that resin acid compounds are pulmonary sensitizers as previously proposed. Changes in the composition of resin acid aerosol derived from heated rosin core solder (compared with the parent material) are described.
Resin acid conversion with CYP105A1: an enzyme with potential for the production of pharmaceutically relevant diterpenoids.[Pubmed:23371760]
Chembiochem. 2013 Mar 4;14(4):467-73.
Cytochrome P450s are very versatile enzymes with great potential for biotechnological applications because of their ability to oxidize unactivated CH bonds. CYP105A1 from Streptomyces griseolus was first described as a herbicide-inducible sulfonylurea hydroxylase, but it is also able to convert other substrates such as vitamin D(3) . To extend the substrate pool of this interesting enzyme further, we screened a small diterpenoid compound library and were able to show the conversion of several resin acids. Binding of abietic acid, dehydroabietic acid, and isopimaric acid to the active site was assayed, and V(max) and K(m) values were calculated. The products were analyzed by NMR spectroscopy and identified as 15-hydroxyabietic acid, 15-Hydroxydehydroabietic acid, and 15,16-epoxyisopimaric acid. As the observed products are difficult to obtain by chemical synthesis, CYP105A1 has proved to be a promising candidate for biotechnological applications that combine bioconversion and chemical synthesis to obtain functionalized resin acids.