Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 7553 - 7560 of 9359 hot products
| Catalog No. | Product Name |
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| BCN6195 | 6-O-Feruloylglucose |
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1. 6-O-(E)-Feruloyl-glucose has scavenging hydroxyl radical activity.
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| BCN6197 | Pomolic acid |
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Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediated intrinsic and death receptor-induced extrinsic pathways. Pomolic acid is a potent inhibitor of the aggregation of human platelets induced by ADP and Epinephrine, exhibits IC50 values close to 60 nM and 20 nM, respectively; pomolic acid does not inhibit human platelet aggregation induced by PAF, collagen, U46619 (thromboxane analogue), TRAP or arachidonic acid; suggests that the hypotensive and platelet anti-aggregating effects of pomolic acid and its potential role in cardiovascular therapy.
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| BCN6198 | Tormentic acid |
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1. Tormentic acid has anti-allodynic action, can inhibit markedly the neuropathic allodynia induced by partial ligation of the sciatic nerve.
2. Tormentic acid has anti-inflammatory activity, it potently inhibits the production of nitric oxide (NO) in RAW 264.7 cells, also suppresses the LPS-stimulated degradation and phosphorylation of inhibitor of kappa B-α (IκB-α), suggests that the anti-inflammatory activity of TA is associated with the down-regulation of iNOS, COX-2, and TNF-α through the negative regulation of the NF-κB pathway in RAW 264.7 cells. 3. Tormentic acid has anticancer, anti-atherogenic properties and minimal toxicity in vivo, it also can reduce vascular smooth muscle cell proliferation and survival. 4. Tormentic acid has protective effect against lipopolysaccharide/D-galactosamine induced fulminant hepatic failure in mice. |
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| BCN6200 | Shikimic acid |
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Shikimic acid(Shikimate), more commonly known as its anionic form shikimate, is an important biochemical intermediate in plants and microorganisms, has great potential for the design and synthesis of enzyme inhibitors. It reversed the H2O2 induced oxidative damage in hepatocytes, probably through the inhibition of NF-κB, with the activation of PI3K/Akt/Nrf2 pathway and reduction of apoptosis by interfering the SAPK/JNK/Bax pathway; it also profoundly inhibited pancreatic lipase activity by 66%, thus providing another valuable therapeutic aspect for treating diet induced obesity in humans.
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| BCN6202 | Isocoronarin D |
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1. Isocoronarin D shows the highest Hb F induction effect of 1.6-fold at 20 microM.
2. Isocoronarin D can activate antioxidant response element (ARE) (EC50 57.6 ± 2.4 uM), it may have potential chemopreventive activity. 3. Isocoronarin D is a main active ingredient for inducing death of the tested cancer cells, it possesses a wide anti-cancer capability. |
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| BCN6203 | Coronarin D ethyl ether |
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1. Coronarin D inhibits NF-KB activation pathway, which leads to inhibition of inflammation,
invasion, and osteoclastogenesis, as well as potentiation of apoptosis. 2. Coronarin D shows promising antifungal activity against C. albicans in vitro. |
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| BCN6204 | Oplodiol |
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1. Oplodiol exhibits noteworthy anti-plasmodial activity against Plasmodium falciparum strains.
2. Oplodiol has a stimulative effect on significantly proliferation and differentiation of culture osteoblasts. 3. Oplodiol shows moderate cytotoxic effects on the human lung adenocarcinoma A549 with IC50 values at 25.5 ug/mL. |
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| BCN6205 | Catalpin |
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Catalpin exhibited mutagenic activity towards Salmonella typhimurium strain TA100 in the presence and absence of rat liver homogenate (S9) mix in Ames' test.
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