Hot Natural Products & Bioactive Compounds

Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey.

Selaginellin F is a natural product from Selaginella pulvinata.

(-)-Fargesol is a nartural product from the flowers buds of Magnolia fargesii,the dried flower buds of M. fargesii, has been used as therapy for nasal empyema and headache.

1. Forbesione has antitumor effects, it combined with 5-FU strongly induced apoptosis in Ham-1 cells.
2. Forbesione exhibits anti-HIV-1 activity.

1. Minimolide F displays inhibitory activity against human nasopharyngeal cancer cells (CNE) with IC(50) values ranging from 1.1 to 20.3 uM.

1. Fucosterol has anti-diabetic activity in vivo, it exhibits an inhibition of sorbitol accumulations in the lenses and causes an inhibition of blood glucose level and glycogen degradation.
2. Fucosterol possesses anti-oxidant and hepatoprotective activities .
3. Fucosterol shows cytotoxic effect against breast and colon carcinoma cell lines.
4. Fucosterol exhibits anti-inflammatory activity which might attribute to inhibition of NO and ROS generation and suppression of the NF-κB pathway.
5. Fucosterol is a dual-LXR agonist that regulates the expression of key genes in cholesterol homeostasis in multiple cell lines without inducing hepatic triglyceride accumulation.
6. Fucosterol has antihistaminic, anticholinergic and antiviral activities.
7. Fucosterol could as an anti-obesity agent, it can inhibit expression of PPARγ and C/EBPα, resulting in a decrease of lipid accumulation in 3T3-L1 pre-adipocytes.

1. Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid‑lowering effects in human HepG2 hepatocellular carcinoma cells treated with free fatty acids (FFAs).

Forsythoside I is a natural product from forsythia suspense (thunb.) vahl.