p-3-Methylamino propyl phenolCAS# 32180-92-0 |
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| Cas No. | 32180-92-0 | SDF | Download SDF |
| PubChem ID | 546966 | Appearance | Cryst. |
| Formula | C10H15NO | M.Wt | 165.23 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 4-[3-(methylamino)propyl]phenol | ||
| SMILES | CNCCCC1=CC=C(C=C1)O | ||
| Standard InChIKey | JLUFUBVFUFUXQA-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C10H15NO/c1-11-8-2-3-9-4-6-10(12)7-5-9/h4-7,11-12H,2-3,8H2,1H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
p-3-Methylamino propyl phenol Dilution Calculator
p-3-Methylamino propyl phenol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 6.0522 mL | 30.2608 mL | 60.5217 mL | 121.0434 mL | 151.3042 mL |
| 5 mM | 1.2104 mL | 6.0522 mL | 12.1043 mL | 24.2087 mL | 30.2608 mL |
| 10 mM | 0.6052 mL | 3.0261 mL | 6.0522 mL | 12.1043 mL | 15.1304 mL |
| 50 mM | 0.121 mL | 0.6052 mL | 1.2104 mL | 2.4209 mL | 3.0261 mL |
| 100 mM | 0.0605 mL | 0.3026 mL | 0.6052 mL | 1.2104 mL | 1.513 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Effects of intraperitoneal administration of the GABAB receptor positive allosteric modulator 2,6-di tert-butyl-4-(2-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) on food intake in non-deprived rats.[Pubmed:22652431]
Eur J Pharmacol. 2012 Sep 5;690(1-3):115-8.
gamma-Aminobutyric acid-(B) (GABA(B)) receptor positive allosteric modulators (PAMs) act on an allosteric site on the GABA(B) receptor to potentiate the effects of GABA and GABA(B) receptor agonists. It has previously been demonstrated that the GABA(B) receptor agonist baclofen increases food intake in non-deprived rats. The aim of this study was to investigate whether the GABA(B) receptor PAM 2,6-di tert-butyl-4-(2-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) would (i) increase food intake, and (ii) potentiate the hyperphagic effects of baclofen in rats. In Experiment 1, the effects of intraperitoneal (i.p.) administration of CGP7930 (1, 6 and 12 mg/kg) was investigated on food intake in non-deprived male Wistar rats. The 12 mg/kg dose of CGP7930 significantly increased cumulative food intake 30, 60 and 120 min (P<0.05, in each case) after administration. The 1 and 6 mg/kg doses were without effect. In Experiment 2, the effects of pretreatment with CGP7930 (6 mg/kg; i.p.) 5 min prior to administration of baclofen (2mg/kg, i.p.) was investigated on 30min cumulative food intake in non-deprived male Wistar rats. Baclofen (2mg/kg) significantly increased food intake compared with vehicle treatment (P<0.01). CGP7930 (6 mg/kg) had no effect on feeding. However, pretreatment with CGP7930 (6 mg/kg) significantly potentiated the hyperphagic effects of baclofen (2mg/kg) (P<0.01). These findings show that CGP7930 increases food intake and enhances the hyperphagic effects of baclofen, and are consistent with in vitro studies that suggest that it potentiates the effects of endogenous GABA and GABA(B) receptor agonists by allosteric modulation of the GABA(B) receptor.
2,4-Diiodo-6-[(propyl-imino)-meth-yl]phenol.[Pubmed:22412661]
Acta Crystallogr Sect E Struct Rep Online. 2012 Mar 1;68(Pt 3):o789.
The title compound, C(10)H(11)I(2)NO, was prepared by the reaction of 3,5-diiodo-salicyl-aldehyde with propyl-amine in ethanol. The mol-ecule adopts an E conformation with respect to the C=N bond and the aromatic ring. The aromatic ring and the imino unit are close to being coplanar, with a dihedral angle of 2.6 (3) degrees between their planes. This planarity is assisted by the formation of an intra-molecular O-Hcdots, three dots, centeredO hydrogen bond.
2-[(Z)-(3-{[(Z)-2-Hy-droxy-3,5-diiodo-benzyl-idene]amino}-propyl-imino)-meth-yl]- 4,6-diiodo-phenol.[Pubmed:22904940]
Acta Crystallogr Sect E Struct Rep Online. 2012 Aug 1;68(Pt 8):o2500.
In the title compound, C(17)H(14)I(4)N(2)O(2), there are two intra-molecular O-Hcdots, three dots, centeredN hydrogen bonds, which make S(6) ring motifs. In the crystal, there are no significant inter-molecular inter-actions present.
2-[(3-Propyl-sulfanyl-5-p-tolyl-4H-1,2,4-triazol-4-yl)imino-meth-yl]phenol.[Pubmed:22058906]
Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2236.
In the title mol-ecule, C(19)H(20)N(4)OS, the two benzene rings form dihedral angles of 16.2 (1) and 12.0 (1) degrees , respectively, with the central triazole ring. In the crystal, inter-molecular O-Hcdots, three dots, centeredN hydrogen bonds link mol-ecules into chains in the [010] direction.
