1-Benzyl-1H-indazol-3-olCAS# 2215-63-6 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 2215-63-6 | SDF | Download SDF |
| PubChem ID | 75181 | Appearance | Powder |
| Formula | C14H12N2O | M.Wt | 224.3 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-benzyl-2H-indazol-3-one | ||
| SMILES | C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=O)N2 | ||
| Standard InChIKey | SXPJFDSMKWLOAB-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C14H12N2O/c17-14-12-8-4-5-9-13(12)16(15-14)10-11-6-2-1-3-7-11/h1-9H,10H2,(H,15,17) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
1-Benzyl-1H-indazol-3-ol Dilution Calculator
1-Benzyl-1H-indazol-3-ol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.4583 mL | 22.2916 mL | 44.5831 mL | 89.1663 mL | 111.4579 mL |
| 5 mM | 0.8917 mL | 4.4583 mL | 8.9166 mL | 17.8333 mL | 22.2916 mL |
| 10 mM | 0.4458 mL | 2.2292 mL | 4.4583 mL | 8.9166 mL | 11.1458 mL |
| 50 mM | 0.0892 mL | 0.4458 mL | 0.8917 mL | 1.7833 mL | 2.2292 mL |
| 100 mM | 0.0446 mL | 0.2229 mL | 0.4458 mL | 0.8917 mL | 1.1146 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Simultaneous determination of benzydamine hydrochloride and five impurities in an oral collutory as a pharmaceutical formulation by high-performance liquid chromatography.[Pubmed:21044418]
J Chromatogr Sci. 2010 Nov;48(10):854-9.
A reversed-phase high-performance liquid chromatographic method for the determination of benzydamine hydrochloride and its impurities 3-dimethylaminopropyl 2-benzylaminobenzoate, 3-dimethylaminopropyl-2-aminobenzoate,1-Benzyl-1H-indazol-3-ol, 1-benzyl-2-(3-dimethylaminopropyl)-1,2-dihydro-3H-indazol-3-one, and 1-benzyl-3-(3-(3-dimethylaminopropyl)-3-methylamino)propoxy-(1)H-indazole in a collutory formulation is developed. The separation is carried out on a Gemini C(18) (250 x 4.6 mm, 5 mum) column using acetonitrile-methanol-ammonium carbonate buffer (10 mM; pH 10.5) (37.5:37.5:25, v/v/v) as mobile phase at a flow rate of 1.0 mL/min, column temperature 30 degrees C, and UV detection at 218 nm. Famotidine is used as an internal standard. The total run-time is less than 15 min. The analytical curves present coefficients of correlation greater than 0.99, and detection limits are calculated for all analytes. Excellent accuracy and precision are obtained for benzydamine hydrochloride. Recoveries vary from 98.25 to 102.8%, and intra- and inter-day precisions, calculated as the percent relative standard deviation, are lower than 2.2%. Specificity and robustness for benzydamine hydrochloride are also determined. The method allows the quantitative determination of benzydamine hydrochloride and its impurities, and it is suitable for routine analysis in quality control laboratories.
