Lethedioside A

CAS# 221289-31-2

Lethedioside A

2D Structure

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Lethedioside A: 5mg $1012 In Stock
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Quality Control of Lethedioside A

3D structure

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Lethedioside A

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Chemical Properties of Lethedioside A

Cas No. 221289-31-2 SDF Download SDF
PubChem ID 10394124 Appearance Powder
Formula C29H34O15 M.Wt 622.6
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-(3,4-dimethoxyphenyl)-7-methoxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
SMILES COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)OC)OC4C(C(C(C(O4)COC5C(C(C(CO5)O)O)O)O)O)O)OC
Standard InChIKey OQEZCWWFGXYLQY-YUYUGGDUSA-N
Standard InChI InChI=1S/C29H34O15/c1-37-13-7-19-22(14(30)9-17(42-19)12-4-5-16(38-2)18(6-12)39-3)20(8-13)43-29-27(36)25(34)24(33)21(44-29)11-41-28-26(35)23(32)15(31)10-40-28/h4-9,15,21,23-29,31-36H,10-11H2,1-3H3/t15-,21-,23+,24-,25+,26-,27-,28+,29-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Lethedioside A

The roots of Aquilaria sinensis (Lour.) Spreng.

Biological Activity of Lethedioside A

DescriptionLethedoside A was either inactive or weakly active against KB tumor cells, in contrast to previously isolated flavones from the same plant.

Protocol of Lethedioside A

Structure Identification
Journal of natural products, 1999, 62(2):241-243.

Five New Flavone 5-O-Glycosides from Lethedon tannaensis:  Lethedosides and Lethediosides.[Reference: WebLink]


METHODS AND RESULTS:
Five new 7-methoxy-flavone 5-O-glycosides were isolated from a cytotoxic MeOH extract of Lethedon tannaensis, and the structures were elucidated by 2D NMR spectral analysis and by chemical methods. Lethedoside A (1), lethedoside B (2), and lethedoside C (3) were 5-O-glucosides of 7,3', 4'-tri-O-methylluteolin, 7,3',4',5'-tetra-O-methyltricetin, and 7,3', 4'-tri-O-methytricetin, respectively; lethediosides A (4) and B (5) and a known compound 6 were 5-O-xylosylglucosides of 7,3', 4'-tri-O-methylluteolin, 7,3',4',5'-tetra-O-methyltricetin, and 7, 4'-di-O-methylapigenin, respectively.
CONCLUSIONS:
These flavonoids were either inactive or weakly active against KB tumor cells, in contrast to previously isolated flavones from the same plant.

Lethedioside A Dilution Calculator

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Lethedioside A Molarity Calculator

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Preparing Stock Solutions of Lethedioside A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6062 mL 8.0308 mL 16.0617 mL 32.1234 mL 40.1542 mL
5 mM 0.3212 mL 1.6062 mL 3.2123 mL 6.4247 mL 8.0308 mL
10 mM 0.1606 mL 0.8031 mL 1.6062 mL 3.2123 mL 4.0154 mL
50 mM 0.0321 mL 0.1606 mL 0.3212 mL 0.6425 mL 0.8031 mL
100 mM 0.0161 mL 0.0803 mL 0.1606 mL 0.3212 mL 0.4015 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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