Erysubin A

CAS# 221150-18-1

Erysubin A

Catalog No. BCN4946----Order now to get a substantial discount!

Product Name & Size Price Stock
Erysubin A: 5mg $799 In Stock
Erysubin A: 10mg Please Inquire In Stock
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Quality Control of Erysubin A

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Chemical structure

Erysubin A

3D structure

Chemical Properties of Erysubin A

Cas No. 221150-18-1 SDF Download SDF
PubChem ID 15838885 Appearance Yellow powder
Formula C20H16O6 M.Wt 352.3
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-hydroxy-6-(4-hydroxyphenyl)-2-(2-hydroxypropan-2-yl)furo[3,2-g]chromen-5-one
SMILES CC(C)(C1=CC2=C(C3=C(C=C2O1)OC=C(C3=O)C4=CC=C(C=C4)O)O)O
Standard InChIKey FJWVISOPPWPZGU-UHFFFAOYSA-N
Standard InChI InChI=1S/C20H16O6/c1-20(2,24)16-7-12-14(26-16)8-15-17(18(12)22)19(23)13(9-25-15)10-3-5-11(21)6-4-10/h3-9,21-22,24H,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Erysubin A

The stem bark of Erythrina caffra Thunb.

Biological Activity of Erysubin A

Description1. Erysubin A , wighteone, and lupalbigenin show promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 uM).
TargetsNO

Erysubin A Dilution Calculator

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Erysubin A Molarity Calculator

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Preparing Stock Solutions of Erysubin A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8385 mL 14.1924 mL 28.3849 mL 56.7698 mL 70.9622 mL
5 mM 0.5677 mL 2.8385 mL 5.677 mL 11.354 mL 14.1924 mL
10 mM 0.2838 mL 1.4192 mL 2.8385 mL 5.677 mL 7.0962 mL
50 mM 0.0568 mL 0.2838 mL 0.5677 mL 1.1354 mL 1.4192 mL
100 mM 0.0284 mL 0.1419 mL 0.2838 mL 0.5677 mL 0.7096 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Erysubin A

Prenylated isoflavones from Cudrania tricuspidata inhibit NO production in RAW 264.7 macrophages and suppress HL-60 cells proliferation.[Pubmed:27649772]

J Asian Nat Prod Res. 2017 May;19(5):510-518.

Inhibitory effects of NO production in RAW 264.7 macrophages guided the isolation of nine prenylated isoflavones, including a new cudraisoflavone L (1) and eight known metabolites furowanin B (2), Erysubin A (3), wighteone (4), lupalbigenin (5), laburnetin (6), isolupalbigenin (7), 6,8-diprenylorobol (8), millewanin H (9) from the leaves of Cudrania tricuspidata. At the concentration of 10 muM, compounds 1, 2, and 4 significantly inhibited NO production with the inhibitory values of 72.5 +/- 2.4, 66.9 +/- 1.8, and 55.4 +/- 2.7%, respectively. In addition, all of isolated compounds 1-9 showed promising cytotoxic effects toward HL-60 cells (IC50 4.3 +/- 0.7 to 18.0 +/- 1.7 muM).

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