2,6-Dimethoxy-1-acetonylquinolCAS# 2215-96-5 |
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3D structure
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| Cas No. | 2215-96-5 | SDF | Download SDF |
| PubChem ID | 241783 | Appearance | Yellow powder |
| Formula | C11H14O5 | M.Wt | 226.2 |
| Type of Compound | Quinones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 4-hydroxy-3,5-dimethoxy-4-(2-oxopropyl)cyclohexa-2,5-dien-1-one | ||
| SMILES | CC(=O)CC1(C(=CC(=O)C=C1OC)OC)O | ||
| Standard InChIKey | KMNCHTPRXWQOIZ-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The barks of Ailanthus altissima
| Description | 1. 2,6-Dimethoxy-1-acetonylquinol shows varying degrees of in vitro antimalarial activity against Plasmodium falciparum. 2. 2,6-Dimethoxy-1-acetonylquinol is devoid of significant cytotoxicity to the human oral epidermoid KB cancer cell line. |
| Targets | Antifection |
2,6-Dimethoxy-1-acetonylquinol Dilution Calculator
2,6-Dimethoxy-1-acetonylquinol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.4209 mL | 22.1043 mL | 44.2087 mL | 88.4173 mL | 110.5217 mL |
| 5 mM | 0.8842 mL | 4.4209 mL | 8.8417 mL | 17.6835 mL | 22.1043 mL |
| 10 mM | 0.4421 mL | 2.2104 mL | 4.4209 mL | 8.8417 mL | 11.0522 mL |
| 50 mM | 0.0884 mL | 0.4421 mL | 0.8842 mL | 1.7683 mL | 2.2104 mL |
| 100 mM | 0.0442 mL | 0.221 mL | 0.4421 mL | 0.8842 mL | 1.1052 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antimalarial compounds from Grewia bilamellata.[Pubmed:16562832]
J Nat Prod. 2006 Mar;69(3):346-50.
Bioassay-directed fractionation led to the isolation of 12 compounds from a sample of the dried leaves, twigs, and stems of Grewia bilamellata. Five of the isolates, 3alpha,20-lupandiol (1), grewin (2), nitidanin (4), 2alpha,3beta-dihydroxy-olean-12-en-28-oic acid (5), and 2,6-Dimethoxy-1-acetonylquinol (6), showed varying degrees of in vitro antimalarial activity against Plasmodium falciparum, but were devoid of significant cytotoxicity to the human oral epidermoid KB cancer cell line. Of the 12 isolates, compounds 1, 2, and 3 (bilagrewin) were determined to be a new triterpene, a new coumarinolignan, and a new neolignan, respectively. Other known compounds isolated in this study were 8-O-4' neolignan guaiacylglycerol-beta-coniferyl ether isomers (threo and erythro), cleomiscosin D, icariol A(2), ciwujiatone, and daucosterol. The structures of 1-3 were elucidated and identified on the basis of spectroscopic data including 1D and 2D NMR analysis.
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