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1-Epideacetylbowdensine

CAS# 101219-55-0

1-Epideacetylbowdensine

2D Structure

Catalog No. BCX0209----Order now to get a substantial discount!

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1-Epideacetylbowdensine: 5mg $1098 In Stock
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3D structure

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1-Epideacetylbowdensine

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Chemical Properties of 1-Epideacetylbowdensine

Cas No. 101219-55-0 SDF Download SDF
PubChem ID 443673 Appearance Powder
Formula C17H21NO5 M.Wt 319.4
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1S,13R,16S,17R)-9-methoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9-triene-16,17-diol
SMILES COC1=C2CN3CCC4(C3CCC(C4O)O)C2=CC5=C1OCO5
Standard InChIKey YDHBKYCFICHVSW-LPOXYFBYSA-N
Standard InChI InChI=1S/C17H21NO5/c1-21-14-9-7-18-5-4-17(13(18)3-2-11(19)16(17)20)10(9)6-12-15(14)23-8-22-12/h6,11,13,16,19-20H,2-5,7-8H2,1H3/t11-,13+,16-,17-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

1-Epideacetylbowdensine Dilution Calculator

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1-Epideacetylbowdensine Molarity Calculator

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Preparing Stock Solutions of 1-Epideacetylbowdensine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1309 mL 15.6544 mL 31.3087 mL 62.6174 mL 78.2718 mL
5 mM 0.6262 mL 3.1309 mL 6.2617 mL 12.5235 mL 15.6544 mL
10 mM 0.3131 mL 1.5654 mL 3.1309 mL 6.2617 mL 7.8272 mL
50 mM 0.0626 mL 0.3131 mL 0.6262 mL 1.2523 mL 1.5654 mL
100 mM 0.0313 mL 0.1565 mL 0.3131 mL 0.6262 mL 0.7827 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 1-Epideacetylbowdensine

Alkaloid production in Crinum moorei cultures.[Pubmed:14640535]

J Nat Prod. 2003 Nov;66(11):1524-6.

The alkaloids cherylline (1), crinamidine (2), crinine (3), epibuphanisine (4), lycorine (5), powelline (6), undulatine (7), 1-Epideacetylbowdensine (8), and 3-O-acetylhamayne (9) were identified in the in vitro propagated bulblets of Crinum moorei. In addition, crinine, powelline, and undulatine were detected in the solidified Murashige and Skoog (MS) medium. The identity of the alkaloids was confirmed by comparing retention times and mass spectra with known samples. Light, as well as benzyladenine (BA) and charcoal supplementation of the tissue culture medium, influenced the levels of specific alkaloids in both the bulblets and media.

Organ-to-organ and seasonal variation in alkaloids from Crinum macowanii.[Pubmed:12385872]

Fitoterapia. 2002 Oct;73(6):490-5.

The distribution and seasonal variation of alkaloids from Crinum macowanii were investigated. The alkaloids lycorine, 1-O-acetyllycorine, crinine, powelline, crinamine, crinamidine, 3-O-acetylhamayne, 1-Epideacetylbowdensine and cherylline were isolated from this plant using gas chromatography. Significant organ-to-organ variations were detected for the alkaloids crinine, lycorine, powelline, crinamidine, 3-O-acetylhamayne and crinamine. Crinine, crinamidine and 1-Epideacetylbowdensine showed significant seasonal variation.

Bioactive alkaloids from Brunsvigia radulosa.[Pubmed:10724185]

Phytochemistry. 2000 Mar;53(5):587-91.

A phytochemical investigation of the bulbs of Brunsvigia radulosa yielded the new alkaloid 1-O-acetylnorpluviine, together with the known structures 1-Epideacetylbowdensine, crinamine, crinine, hamayne, lycorine, anhydrolycorin-6-one and sternbergine. All structures were established by spectroscopic evidence. Some of the 13C assignments which were reported for crinamine and hamayne were corrected by means of 2D NMR techniques. In order to provide a further structure for biological testing, crinamine was converted to apohaemanthamine. The alkaloids were tested for activity against two strains of cultured Plasmodium falciparum and for cytotoxicity with BL6 mouse melanoma cells.

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