Home >> Research Area >>Natural Products>>Alkaloids>> 1-Methoxyindole-3-carboxylic acid

1-Methoxyindole-3-carboxylic acid

CAS# 91913-76-7

1-Methoxyindole-3-carboxylic acid

Catalog No. BCN3946----Order now to get a substantial discount!

Product Name & Size Price Stock
1-Methoxyindole-3-carboxylic acid: 5mg $725 In Stock
1-Methoxyindole-3-carboxylic acid: 10mg Please Inquire In Stock
1-Methoxyindole-3-carboxylic acid: 20mg Please Inquire Please Inquire
1-Methoxyindole-3-carboxylic acid: 50mg Please Inquire Please Inquire
1-Methoxyindole-3-carboxylic acid: 100mg Please Inquire Please Inquire
1-Methoxyindole-3-carboxylic acid: 200mg Please Inquire Please Inquire
1-Methoxyindole-3-carboxylic acid: 500mg Please Inquire Please Inquire
1-Methoxyindole-3-carboxylic acid: 1000mg Please Inquire Please Inquire

Quality Control of 1-Methoxyindole-3-carboxylic acid

Number of papers citing our products

Chemical structure

1-Methoxyindole-3-carboxylic acid

3D structure

Chemical Properties of 1-Methoxyindole-3-carboxylic acid

Cas No. 91913-76-7 SDF Download SDF
PubChem ID 124476 Appearance Powder
Formula C10H9NO3 M.Wt 191.2
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-methoxyindole-3-carboxylic acid
SMILES CON1C=C(C2=CC=CC=C21)C(=O)O
Standard InChIKey NYXZLEZAQMDQPX-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 1-Methoxyindole-3-carboxylic acid

The herbs of Isatis indigotica

Biological Activity of 1-Methoxyindole-3-carboxylic acid

DescriptionStandard reference
In vitro

In vitro O-demethylation from a heterocyclic nitrogen: a novel metabolic reaction?[Pubmed: 1949889]

Xenobiotica. 1991 May;21(5):569-74.


METHODS AND RESULTS:
1. O-Demethylation of 1-Methoxyindole-3-carboxylic acid, in vitro, by determination of liberated formaldehyde, has been demonstrated using fortified 15,000 g rat liver supernatant fraction. 2. Results have been compared to those similarly obtained with a standard O-demethylation substrate, 4-nitroanisole, to substantiate and quantify the extent of the reaction. 3. Km values for 4-nitroanisole and methoxyindole-3-carboxylic acid were 8.9 and 6.5 mM, while Vmax values were 4.9, and 5.2 nmol HCHO produced/mg protein per min.
CONCLUSIONS:
4. The significance of the metabolic O-demethylation reaction for N-methoxyindoles as a novel metabolic pathway is discussed in terms of pharmacological activity and biological reactivity.

1-Methoxyindole-3-carboxylic acid Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

1-Methoxyindole-3-carboxylic acid Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of 1-Methoxyindole-3-carboxylic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.2301 mL 26.1506 mL 52.3013 mL 104.6025 mL 130.7531 mL
5 mM 1.046 mL 5.2301 mL 10.4603 mL 20.9205 mL 26.1506 mL
10 mM 0.523 mL 2.6151 mL 5.2301 mL 10.4603 mL 13.0753 mL
50 mM 0.1046 mL 0.523 mL 1.046 mL 2.0921 mL 2.6151 mL
100 mM 0.0523 mL 0.2615 mL 0.523 mL 1.046 mL 1.3075 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on 1-Methoxyindole-3-carboxylic acid

In vitro O-demethylation from a heterocyclic nitrogen: a novel metabolic reaction?[Pubmed:1949889]

Xenobiotica. 1991 May;21(5):569-74.

1. O-Demethylation of 1-Methoxyindole-3-carboxylic acid, in vitro, by determination of liberated formaldehyde, has been demonstrated using fortified 15,000 g rat liver supernatant fraction. 2. Results have been compared to those similarly obtained with a standard O-demethylation substrate, 4-nitroanisole, to substantiate and quantify the extent of the reaction. 3. Km values for 4-nitroanisole and methoxyindole-3-carboxylic acid were 8.9 and 6.5 mM, while Vmax values were 4.9, and 5.2 nmol HCHO produced/mg protein per min. 4. The significance of the metabolic O-demethylation reaction for N-methoxyindoles as a novel metabolic pathway is discussed in terms of pharmacological activity and biological reactivity.

Keywords:

1-Methoxyindole-3-carboxylic acid,91913-76-7,Natural Products, buy 1-Methoxyindole-3-carboxylic acid , 1-Methoxyindole-3-carboxylic acid supplier , purchase 1-Methoxyindole-3-carboxylic acid , 1-Methoxyindole-3-carboxylic acid cost , 1-Methoxyindole-3-carboxylic acid manufacturer , order 1-Methoxyindole-3-carboxylic acid , high purity 1-Methoxyindole-3-carboxylic acid

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: