1-Methoxyindole-3-carboxylic acidCAS# 91913-76-7 |
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| Cas No. | 91913-76-7 | SDF | Download SDF |
| PubChem ID | 124476 | Appearance | Powder |
| Formula | C10H9NO3 | M.Wt | 191.2 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-methoxyindole-3-carboxylic acid | ||
| SMILES | CON1C=C(C2=CC=CC=C21)C(=O)O | ||
| Standard InChIKey | NYXZLEZAQMDQPX-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Standard reference |
| In vitro | In vitro O-demethylation from a heterocyclic nitrogen: a novel metabolic reaction?[Pubmed: 1949889]Xenobiotica. 1991 May;21(5):569-74.
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1-Methoxyindole-3-carboxylic acid Dilution Calculator
1-Methoxyindole-3-carboxylic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 5.2301 mL | 26.1506 mL | 52.3013 mL | 104.6025 mL | 130.7531 mL |
| 5 mM | 1.046 mL | 5.2301 mL | 10.4603 mL | 20.9205 mL | 26.1506 mL |
| 10 mM | 0.523 mL | 2.6151 mL | 5.2301 mL | 10.4603 mL | 13.0753 mL |
| 50 mM | 0.1046 mL | 0.523 mL | 1.046 mL | 2.0921 mL | 2.6151 mL |
| 100 mM | 0.0523 mL | 0.2615 mL | 0.523 mL | 1.046 mL | 1.3075 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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In vitro O-demethylation from a heterocyclic nitrogen: a novel metabolic reaction?[Pubmed:1949889]
Xenobiotica. 1991 May;21(5):569-74.
1. O-Demethylation of 1-Methoxyindole-3-carboxylic acid, in vitro, by determination of liberated formaldehyde, has been demonstrated using fortified 15,000 g rat liver supernatant fraction. 2. Results have been compared to those similarly obtained with a standard O-demethylation substrate, 4-nitroanisole, to substantiate and quantify the extent of the reaction. 3. Km values for 4-nitroanisole and methoxyindole-3-carboxylic acid were 8.9 and 6.5 mM, while Vmax values were 4.9, and 5.2 nmol HCHO produced/mg protein per min. 4. The significance of the metabolic O-demethylation reaction for N-methoxyindoles as a novel metabolic pathway is discussed in terms of pharmacological activity and biological reactivity.
