Saikosaponin H

CAS# 91990-63-5

Saikosaponin H

2D Structure

Catalog No. BCN7808----Order now to get a substantial discount!

Product Name & Size Price Stock
Saikosaponin H: 5mg $161 In Stock
Saikosaponin H: 10mg Please Inquire In Stock
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Quality Control of Saikosaponin H

3D structure

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Saikosaponin H

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Chemical Properties of Saikosaponin H

Cas No. 91990-63-5 SDF Download SDF
PubChem ID 21636280 Appearance Powder
Formula C48H78O17 M.Wt 927.12
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3R,4R,5R,6S)-2-[(2R,3S,4R,5R,6R)-6-[[(3S,4aR,6aR,6bS,8S,8aS,14aR,14bS)-8-hydroxy-8a-(hydroxymethyl)-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,14a-dodecahydropicen-3-yl]oxy]-4,5-dihydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
SMILES CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3CCC4(C(C3(C)C)CCC5(C4C=CC6=C7CC(CCC7(C(CC65C)O)CO)(C)C)C)C)COC8C(C(C(C(O8)CO)O)O)O)O)O)O
Standard InChIKey PYJMYPPFWASOJX-XMRFJGCSSA-N
Standard InChI InChI=1S/C48H78O17/c1-22-31(52)33(54)37(58)41(61-22)65-39-26(20-60-40-36(57)34(55)32(53)25(19-49)62-40)63-42(38(59)35(39)56)64-30-12-13-45(6)27(44(30,4)5)11-14-46(7)28(45)10-9-23-24-17-43(2,3)15-16-48(24,21-50)29(51)18-47(23,46)8/h9-10,22,25-42,49-59H,11-21H2,1-8H3/t22-,25+,26+,27-,28+,29-,30-,31-,32+,33+,34-,35+,36+,37+,38+,39+,40+,41-,42-,45-,46+,47+,48+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Saikosaponin H

The roots of Bupleurum chinense

Biological Activity of Saikosaponin H

DescriptionSaikosaponin H is a natural product from Bupleurum chinense.

Protocol of Saikosaponin H

Structure Identification
Journal of Pharmaceutical Investigation,2008,38(1):57-61.

Determination of saikosaponin derivatives in Bupleuri Radix using HPLC-ELSD.[Reference: WebLink]


METHODS AND RESULTS:
A HPLC-ELSD method was developed to determine saikosaponin derivatives from Bupleuri Radix. Eight saikosaponins, saikosaponin c, saikosaponin i, Saikosaponin H, saikosaponin a, saikosaponin b1, saikosaponin g, saikosaponin b2, and saikosaponin d, were analyzed under optimized HPLC conditions [column: Eclipse XDB (i.d., ; mobile phase: with 0.1% COOH (v/v) for solvent A and AcCN with 0.1% COOH (v/v) for solvent B, gradient elution; flow rate: 1mL/min; injection volume: ]. Good linearity was achieved in the range from 62.5 to for each compound, and intra-day precision and accuracy at each concentration level varied between 0.05 and 5.45% and between 93.9 and 109.6%, respectively, whereas those for inter-day variations were between 0.91 to 2.73% and 94.3 to 106.1%. This HPLC-ELSD method was applied for the determination of sakosaponins from Bupleuri Radix samples, and saikosaponin a , c and d were observed as major compounds. The other saikosaponins were shown under limit of quantification level thus couldn't be quantified.
CONCLUSIONS:
The present study suggested that the introduced HPLC-ELSD method is selective and reliable, and not only saikosaponin a, but also saikosaponin c and d should be employed as the standard markers for Bupleuri Radix.

Saikosaponin H Dilution Calculator

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Saikosaponin H Molarity Calculator

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Preparing Stock Solutions of Saikosaponin H

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0786 mL 5.393 mL 10.7861 mL 21.5722 mL 26.9652 mL
5 mM 0.2157 mL 1.0786 mL 2.1572 mL 4.3144 mL 5.393 mL
10 mM 0.1079 mL 0.5393 mL 1.0786 mL 2.1572 mL 2.6965 mL
50 mM 0.0216 mL 0.1079 mL 0.2157 mL 0.4314 mL 0.5393 mL
100 mM 0.0108 mL 0.0539 mL 0.1079 mL 0.2157 mL 0.2697 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Description

Saikosaponin H is a saikosaponin derived from the herb Radix bupleuri.

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