Rubrisandrin ACAS# 919289-30-8 |
2D Structure
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
Cas No. | 919289-30-8 | SDF | Download SDF |
PubChem ID | 16099402 | Appearance | Cryst. |
Formula | C22H28O6 | M.Wt | 388.5 |
Type of Compound | Lignans | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
SMILES | CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3CC1C)OC)OC)O)OC)OC)O | ||
Standard InChIKey | YTAKUZMOQQARQX-NEPJUHHUSA-N | ||
Standard InChI | InChI=1S/C22H28O6/c1-11-7-13-9-15(23)20(26-4)22(28-6)18(13)17-14(8-12(11)2)10-16(25-3)21(27-5)19(17)24/h9-12,23-24H,7-8H2,1-6H3/t11-,12+/m1/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | 1. Rubrisandrin A is an anti-HIV agent. |
Targets | HIV |
Rubrisandrin A Dilution Calculator
Rubrisandrin A Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 2.574 mL | 12.87 mL | 25.74 mL | 51.4801 mL | 64.3501 mL |
5 mM | 0.5148 mL | 2.574 mL | 5.148 mL | 10.296 mL | 12.87 mL |
10 mM | 0.2574 mL | 1.287 mL | 2.574 mL | 5.148 mL | 6.435 mL |
50 mM | 0.0515 mL | 0.2574 mL | 0.5148 mL | 1.0296 mL | 1.287 mL |
100 mM | 0.0257 mL | 0.1287 mL | 0.2574 mL | 0.5148 mL | 0.6435 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Ro 15-4513
Catalog No.:BCC7230
CAS No.:91917-65-6
- Atrial natriuretic factor (1-28) (human, porcine)
Catalog No.:BCC5839
CAS No.:91917-63-4
- 1-Methoxyindole-3-carboxylic acid
Catalog No.:BCN3946
CAS No.:91913-76-7
- 19-[(beta-D-glucopyranosyl)oxy]-19-oxo-ent-labda-8(17),13-dien-16,15-olide
Catalog No.:BCN1308
CAS No.:919120-78-8
- GPi 688
Catalog No.:BCC6091
CAS No.:918902-32-6
- TH-302
Catalog No.:BCC1998
CAS No.:918633-87-1
- PLX-4720
Catalog No.:BCC1280
CAS No.:918505-84-7
- BRAF inhibitor
Catalog No.:BCC1436
CAS No.:918505-61-0
- Vemurafenib (PLX4032, RG7204)
Catalog No.:BCC1269
CAS No.:918504-65-1
- 5,7,4'-Trimethoxyafzelechin
Catalog No.:BCN7933
CAS No.:918428-88-3
- Cefdinir
Catalog No.:BCC3747
CAS No.:91832-40-5
- UCL 2077
Catalog No.:BCC7446
CAS No.:918311-87-2
- AZD1283
Catalog No.:BCC5370
CAS No.:919351-41-0
- Zatebradine hydrochloride
Catalog No.:BCC7286
CAS No.:91940-87-3
- Buergerinin B
Catalog No.:BCN4555
CAS No.:919769-83-8
- Saikosaponin H
Catalog No.:BCN7808
CAS No.:91990-63-5
- OF-1
Catalog No.:BCC5579
CAS No.:919973-83-4
- o-Acetoacetaniside
Catalog No.:BCC9107
CAS No.:92-15-9
- 6-Methylcoumarin
Catalog No.:BCN6906
CAS No.:92-48-8
- Scopoletin
Catalog No.:BCN4470
CAS No.:92-61-5
- Phenothiazine
Catalog No.:BCC4701
CAS No.:92-84-2
- 4,4'-Biphenol
Catalog No.:BCC8654
CAS No.:92-88-6
- 4-Acetylbiphenyl
Catalog No.:BCC8673
CAS No.:92-91-1
- 4-Biphenylcarboxylic acid
Catalog No.:BCC8701
CAS No.:92-92-2
Rubrisandrins A and B, lignans and related anti-HIV compounds from Schisandra rubriflora.[Pubmed:17190445]
J Nat Prod. 2006 Dec;69(12):1697-701.
Bioactivity-directed fractionation of an ethanolic extract of the fruits of Schisandra rubriflora led to the isolation and identification of dibenzocyclooctadiene lignans including the new lignans rubrisandrins A (1a + 1b) and B (2) and the known lignans gomisin J (3), (+/-)-gomisin M1 (4), (+)-gomisin M2 (5), schisanhenol (6), deoxyschisandrin, schisantherin B, schisandrin, tigloylgomisin P, gomisin O, angeloylgomisin P, and epigomisin O. Their structure and stereochemistry were determined by spectroscopic methods, including 2D-NMR techniques. Compounds 1 and 3-6 were active as anti-HIV agents. (+/-)-Gomisin M1 (4) exhibited the most potent anti-HIV activity, with EC50 and therapeutic index (TI) values of <0.65 microM and >68, respectively.
Evaluation of cytotoxic activity of Schisandra chinensis lignans.[Pubmed:20458670]
Planta Med. 2010 Oct;76(15):1672-7.
Using exhaustive chromatographic separation we have isolated (-)-tigloyl-deangeloyl-gomisin F as a novel dibenzocyclooctadiene lignan from schisandra chinensis. With the help of HPLC, we further isolated (+)-schisandrin, (+)-deoxyschisandrin, (+)-gamma-schisandrin, (-)-gomisin J, (+)-gomisin A, (-)-gomisin N, (-)-tigloyl-gomisin P, (-)-wuweizisu C, (-)-gomisin D, Rubrisandrin A, (-)-gomisin G, (+)-gomisin K (3) and (-)-schisantherin C. A full NMR description of (-)-schisantherin C was carried out with the aim to confirm previous reports of its structure. Compounds isolated were identified on the basis of UV, IR, (1)H- and (13)C-NMR and MS. The cytotoxicity of lignans was tested for the BY-2 cell line alone and as a synergistic effect with the cytotoxic agent camptothecin. Lignans showed various toxicity and synergistic and antagonistic effects on camptothecin-induced cytotoxicity. Cytotoxicity against colon cancer cell line LoVo was also tested.