5,7,4'-TrimethoxyafzelechinCAS# 918428-88-3 |
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| Cas No. | 918428-88-3 | SDF | Download SDF |
| PubChem ID | 16036403 | Appearance | Powder |
| Formula | C18H20O5 | M.Wt | 316.35 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2R,3S)-5,7-dimethoxy-2-(4-methoxyphenyl)-3,4-dihydro-2H-chromen-3-ol | ||
| SMILES | COC1=CC=C(C=C1)C2C(CC3=C(C=C(C=C3O2)OC)OC)O | ||
| Standard InChIKey | NMLBREXWQRPOJH-MAUKXSAKSA-N | ||
| Standard InChI | InChI=1S/C18H20O5/c1-20-12-6-4-11(5-7-12)18-15(19)10-14-16(22-3)8-13(21-2)9-17(14)23-18/h4-9,15,18-19H,10H2,1-3H3/t15-,18+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Celastrus orbiculatus
| Description | 5,7,4'-Trimethoxyafzelechin is a natural product from Celastrus orbiculatus. |
| Structure Identification | J Oleo Sci. 2008;57(8):431-5.Alpha-glucosidase inhibitor from Bergenia ligulata.[Pubmed: 18622126]Inhibitory compound of alpha-glucosidase activity, (+)-afzelechin (1), was isolated from rhizomes of Bergenia ligulata.
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5,7,4'-Trimethoxyafzelechin Dilution Calculator
5,7,4'-Trimethoxyafzelechin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1611 mL | 15.8053 mL | 31.6106 mL | 63.2211 mL | 79.0264 mL |
| 5 mM | 0.6322 mL | 3.1611 mL | 6.3221 mL | 12.6442 mL | 15.8053 mL |
| 10 mM | 0.3161 mL | 1.5805 mL | 3.1611 mL | 6.3221 mL | 7.9026 mL |
| 50 mM | 0.0632 mL | 0.3161 mL | 0.6322 mL | 1.2644 mL | 1.5805 mL |
| 100 mM | 0.0316 mL | 0.1581 mL | 0.3161 mL | 0.6322 mL | 0.7903 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Alpha-glucosidase inhibitor from Bergenia ligulata.[Pubmed:18622126]
J Oleo Sci. 2008;57(8):431-5.
Inhibitory compound of alpha-glucosidase activity, (+)-afzelechin (1), was isolated from rhizomes of Bergenia ligulata. The structure was identified by IR, EI-MS, (1)H and (13)C NMR spectroscopy. The ID(50) (50% inhibition dose) value of compound 1 was 0.13 mM. To investigate the structure-activity relationship, (+)-afzelechin tetraacetate (2), (+)-5,7,4'-trimethoxyafzelechin (3), (+)-tetramethoxyafzelechin (4), and (+)-3-acetyl-5,7,4'-trimethoxyafzelechin (5) as the derivatives of compound 1 were evaluated as well.
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