1-Oxo-4-hydroxy-2-en-4-ethylcyclohexa-5,8-olideCAS# 55604-88-1 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 55604-88-1 | SDF | Download SDF |
PubChem ID | 85844078 | Appearance | Powder |
Formula | C8H8O4 | M.Wt | 168.2 |
Type of Compound | Miscellaneous | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | 3a-hydroxy-7,7a-dihydro-3H-1-benzofuran-2,6-dione | ||
SMILES | C1C2C(CC(=O)O2)(C=CC1=O)O | ||
Standard InChIKey | USTIRZSUTZHBAK-UHFFFAOYSA-N | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
1-Oxo-4-hydroxy-2-en-4-ethylcyclohexa-5,8-olide Dilution Calculator
1-Oxo-4-hydroxy-2-en-4-ethylcyclohexa-5,8-olide Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 5.9453 mL | 29.7265 mL | 59.453 mL | 118.9061 mL | 148.6326 mL |
5 mM | 1.1891 mL | 5.9453 mL | 11.8906 mL | 23.7812 mL | 29.7265 mL |
10 mM | 0.5945 mL | 2.9727 mL | 5.9453 mL | 11.8906 mL | 14.8633 mL |
50 mM | 0.1189 mL | 0.5945 mL | 1.1891 mL | 2.3781 mL | 2.9727 mL |
100 mM | 0.0595 mL | 0.2973 mL | 0.5945 mL | 1.1891 mL | 1.4863 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Alverine Citrate
Catalog No.:BCC4619
CAS No.:5560-59-8
- Alliin
Catalog No.:BCN3869
CAS No.:556-27-4
- H-D-Tyr-OH
Catalog No.:BCC3134
CAS No.:556-02-5
- Acesulfame Potassium
Catalog No.:BCC4755
CAS No.:55589-62-3
- Agrimol B
Catalog No.:BCN5017
CAS No.:55576-66-4
- Boc-Phe(4-NH2)-OH
Catalog No.:BCC3153
CAS No.:55533-24-9
- H-1-Nal-OH
Catalog No.:BCC3282
CAS No.:55516-54-6
- Biondinin C
Catalog No.:BCN5744
CAS No.:55511-08-5
- 6-Shogaol
Catalog No.:BCN6288
CAS No.:555-66-8
- CCCP
Catalog No.:BCC5658
CAS No.:555-60-2
- Tritetradecanoin
Catalog No.:BCN8389
CAS No.:555-45-3
- Methyldopa
Catalog No.:BCC4676
CAS No.:555-30-6
- Aristololactam II
Catalog No.:BCN8095
CAS No.:55610-00-9
- Cepharadione A
Catalog No.:BCN3950
CAS No.:55610-01-0
- Cepharadione B
Catalog No.:BCN6524
CAS No.:55610-02-1
- Syneilesine
Catalog No.:BCN2144
CAS No.:55652-65-8
- Deltonin
Catalog No.:BCC8933
CAS No.:55659-75-1
- Boc-D-Thr-OH
Catalog No.:BCC3453
CAS No.:55674-67-4
- TCN 213
Catalog No.:BCC6123
CAS No.:556803-08-8
- 1-Octacosanol
Catalog No.:BCN2973
CAS No.:557-61-9
- (24S)-24,25-Dihydroxyvitamin D3
Catalog No.:BCC1290
CAS No.:55700-58-8
- Secalciferol
Catalog No.:BCC1942
CAS No.:55721-11-4
- Salinomycin sodium salt
Catalog No.:BCC1917
CAS No.:55721-31-8
- Boc-D-Ile-OH
Catalog No.:BCC3407
CAS No.:55721-65-8
Two new sesquiterpenes from Chloranthus japonicus Sieb.[Pubmed:27399937]
Nat Prod Res. 2016 Nov;30(21):2476-82.
Two new sesquiterpenes, namely, 1beta,10beta-dihydroxy-eremophil-7(11), 8-dien-12,8-olide (1) and 8,12-epoxy-1beta-hydroxyeudesm-3,7,11-trien-9-one (2), together with three known sesquiterpenoids, shizukolidol (3), 4alpha-hydroxy-5alpha(H)-8beta-methoxy-eudesm-7(11)-en-12,8-olide (4), and neolitacumone B (5), and two known monoterpenes, (3R,4S,6R)-p-menth-1-en-3,6-diol (6) and (R)-p-menth-1-en-4,7-diol (7), were isolated from the whole plant of Chloranthus japonicus Sieb. Their structures were elucidated on the basis of spectroscopic data analysis and comparison with those of related known compounds. Compounds 4-7 were isolated from this plant for the first time.
Sesquiterpenoids from Chloranthus henryi and their anti-neuroinflammatory activities.[Pubmed:24934677]
Chem Biodivers. 2014 Jun;11(6):919-28.
Five new and seven known mono-sesquiterpenoids (1-5 and 6-12, resp.) together with five known lindenane-type disesquiterpenoids, 13-17, were isolated from the whole plant of Chloranthus henryi. Based on spectroscopic methods, the new structures were established to be (5S,6R,8S,10R)-6-hydroxyeudesma-4(15),7(11)-diene-12,8-olide (1), 6alpha-hydroxyeudesma-4(15),7(11),8(9)-triene-12,8-olide (2), 8,12-epoxy-1beta-hydroxyeudesma-4(15),7,11-trien-6-one (3), 12-oxochloraniolide A (4), and (4alpha)-8-hydroxy-12-norcardina-6,8,10-trien-11-one (5), respectively. Among the isolates, compound 2, zederone epoxide (8), spicachlorantin G (13), chloramultilide A (14), shizukaol B (15), and spicachlorantin B (17) showed significant anti-neuroinflammatory effects by inhibiting nitric-oxide (NO) production in lipopolysaccharide (LPS)-stimulated murine BV-2 microglial cells with relatively low cytotoxicity.
DNA Topoisomerase Inhibitory Activity of Constituents from the Flowers of Inula japonica.[Pubmed:26936053]
Chem Pharm Bull (Tokyo). 2016;64(3):276-81.
Fourteen compounds were isolated from the flowers of Inula japonica THUNB. (Asteraceae), including two new compounds, (1S,2S,4S,5S,8S,10R)-2-acetoxy-4,3-dihydroxy-pseudoguai-7(11)-en-12,8-olide (1) and (1S,2S,4S,5S,8S,10R)-2,4,13-trihydroxy-pseudoguai-7(11)-en-12,8-olide (2), and twelve known compounds, budlein B (3), 6beta-hydroxytomentosin (4), 6-deacetoxybritanin (5), 4-epipulchellin (6), britanin (7), tomentosin (8), (+)-dihydroquercetin (9), (-)-syringaresinol (10), quercetagetin 3,4'-dimethyl ether (11), luteolin (12), britanin G (13) and inuchinenolide C (14). Structures of 1 and 2 were determined based on one and two dimensional (1D)- and (2D)-NMR data and Mosher's esterification method. Compounds 9 and 12 showed inhibitory activities toward DNA topoisomerase I with IC50 values of 55.7 and 37.0 microM, respectively, compared to camptothecin (CPT) with an IC50 of 24.5 microM. Compounds 7-9 and 11-14 exhibited more potent inhibitory activity against topoisomerases II with IC50 values of 6.9, 3.8, 3.0, 6.9, 10.0, 14.7 and 13.8 microM, respectively, than that of etoposide (VP-16) with an IC50 of 26.9 microM. Compounds 4-7 and 10-14 exhibited weak cytotoxicities to the selected cancer cell lines.
[Chemical constituents from roots of Ligularia intermedia].[Pubmed:26087552]
Zhongguo Zhong Yao Za Zhi. 2015 Mar;40(5):894-6.
A new sesquiterpenoid, 8alpha-hydroxy-6beta-methoxy-1-oxoeremophila-7 (11), 9 (10) -diene-12, 8-olide (1) and five known compounds, petasin (2), caffeic acid (3), hepta-cosanol (4), beta-sitosterol (5) and beta-daucosterol (6) have been isolated from the roots of Ligularia intermedia. The compounds were isolated by column chromatography on silica gel and Sephadex LH-20, and identified based on spectral analyses (MS, 1H-NMR, 13C-NMR).
New 12,8-Eudesmanolides from Eutypella sp. 1-15.[Pubmed:28951605]
J Antibiot (Tokyo). 2017 Oct;70(10):1029-1032.
Four new 12,8-Eudesmanolides (1-4) and one known compound 5 named 13-Hydroxy-3,7(11)-eudesmadien-12,8-olide, were isolated from a mangrove rhizosphere-derived fungus Eutypella sp. 1-15. Their structures with absolute stereochemistry were determined by the comprehensive spectroscopic data, experimental and calculated ECD analysis. Compound 1 exhibited potent anticancer activity against JEKO-1 and HepG2 with IC50 values of 8.4 and 28.5 muM, respectively. Additionally, compound 1 also showed moderate antimicrobial activity.