2,3-DCPE hydrochlorideBcl-XL protein expression downregulator CAS# 418788-90-6 |
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Quality Control & MSDS
3D structure
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| Cas No. | 418788-90-6 | SDF | Download SDF |
| PubChem ID | 2250974 | Appearance | Powder |
| Formula | C11H16Cl2NO2+ | M.Wt | 265.2 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble to 100 mM in sterile water | ||
| Chemical Name | 3-(2,3-dichlorophenoxy)propyl-(2-hydroxyethyl)azanium | ||
| SMILES | C1=CC(=C(C(=C1)Cl)Cl)OCCC[NH2+]CCO | ||
| Standard InChIKey | QVEIRCZEBQRCTR-UHFFFAOYSA-O | ||
| Standard InChI | InChI=1S/C11H15Cl2NO2/c12-9-3-1-4-10(11(9)13)16-8-2-5-14-6-7-15/h1,3-4,14-15H,2,5-8H2/p+1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
2,3-DCPE hydrochloride Dilution Calculator
2,3-DCPE hydrochloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.7707 mL | 18.8537 mL | 37.7074 mL | 75.4148 mL | 94.2685 mL |
| 5 mM | 0.7541 mL | 3.7707 mL | 7.5415 mL | 15.083 mL | 18.8537 mL |
| 10 mM | 0.3771 mL | 1.8854 mL | 3.7707 mL | 7.5415 mL | 9.4268 mL |
| 50 mM | 0.0754 mL | 0.3771 mL | 0.7541 mL | 1.5083 mL | 1.8854 mL |
| 100 mM | 0.0377 mL | 0.1885 mL | 0.3771 mL | 0.7541 mL | 0.9427 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Selectively induces apoptosis and downregulates Bcl-XL protein expression in various human cancer cells versus normal cells in vitro. IC50 values are 0.89 and 12.6 μM for LoVo human colon cancer cell line and normal human fibroblasts respectively. Induces p21 expression and S-phase arrest in cancer cells via ERK-mediated pathways.
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