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Mangiferolic acid

CAS# 4184-34-3

Mangiferolic acid

2D Structure

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Mangiferolic acid

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Chemical Properties of Mangiferolic acid

Cas No. 4184-34-3 SDF Download SDF
PubChem ID 45270099 Appearance Powder
Formula C30H48O3 M.Wt 456.71
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(CCC=C(C)C(=O)O)C1CCC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)O)C)C
Standard InChIKey CYHOTEDWAOHQLA-HCJSCJCOSA-N
Standard InChI InChI=1S/C30H48O3/c1-19(8-7-9-20(2)25(32)33)21-12-14-28(6)23-11-10-22-26(3,4)24(31)13-15-29(22)18-30(23,29)17-16-27(21,28)5/h9,19,21-24,31H,7-8,10-18H2,1-6H3,(H,32,33)/b20-9+/t19-,21-,22+,23+,24+,27-,28+,29-,30+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Mangiferolic acid

The herbs of Mangifera indica L.

Biological Activity of Mangiferolic acid

In vitro

Characterisation of triterpenes and new phenolic lipids in Cameroonian propolis.[Pubmed: 25104230]

Phytochemistry. 2014 Oct;106:156-63.


METHODS AND RESULTS:
Chemical investigation of a sample of propolis originating from North-Western Cameroon led to the isolation of thirteen alk(en)ylphenols (1-13) (inseparable mixture) along with α-amyrin (14), β-amyrin (15), lupeol (16), cycloartenol (17), mangiferonic acid (18), ambonic acid (19), Mangiferolic acid (20), ambolic acid (21), isoMangiferolic acid (22) and nine alk(en)ylresorcinols (23-31) (inseparable mixture). All compounds were identified following analysis of their spectroscopic data and comparison with previously published reports. Compounds (8), (12), (13) and (30) are new natural products. GC-MS analysis carried out on the alk(en)ylphenol and alk(en)ylresorcinol mixtures (dimethyl disulphide trimethylsilyl derivatives) revealed the presence of saturated and mono-unsaturated compounds with side chain lengths ranging from C11 to C19 and C15 to C19, respectively. The position of the double bond in mono-unsaturated derivatives was established from the characteristic fragments resulting from the cleavage of the bond between the two methylthio-substituted carbons. The most abundant compound in each mixture was 3-(12'Z-heptadecenyl)-phenol (10) and 5-(12'Z-heptadecenyl)-resorcinol (29).
CONCLUSIONS:
This study is the first to report the presence of triterpenes (except for lupeol) and phenolic lipids, including eighteen compounds previously unreported in bee glue, in an African sample.

Protocol of Mangiferolic acid

Structure Identification
Yao Xue Xue Bao. 1997 Sep;32(9):704-7.

Triterpene acids from the barks of Illicium difengpi[Pubmed: 11596298]


METHODS AND RESULTS:
Four compounds were isolated from the traditional Chinese medicine "Difengpi", barks of Illicium difengpi K.I.B. et K.I.M. They were identified as 3 beta-O-acetyl-Mangiferolic acid (I), mangiferonic acid (II), Mangiferolic acid (III) and butulinic acid (IV) by physico-chemical constants and spectral analyses (UV, IR, EIMS, 1HNMR, 13CNMR, NOEDE and 2D NMR).
CONCLUSIONS:
Compound I is a new compound. These triterpene acids (I-IV) were isolated from Illicium genus for the first time.

Mangiferolic acid Dilution Calculator

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Mangiferolic acid Molarity Calculator

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Preparing Stock Solutions of Mangiferolic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1896 mL 10.9479 mL 21.8957 mL 43.7915 mL 54.7393 mL
5 mM 0.4379 mL 2.1896 mL 4.3791 mL 8.7583 mL 10.9479 mL
10 mM 0.219 mL 1.0948 mL 2.1896 mL 4.3791 mL 5.4739 mL
50 mM 0.0438 mL 0.219 mL 0.4379 mL 0.8758 mL 1.0948 mL
100 mM 0.0219 mL 0.1095 mL 0.219 mL 0.4379 mL 0.5474 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Mangiferolic acid

Characterisation of triterpenes and new phenolic lipids in Cameroonian propolis.[Pubmed:25104230]

Phytochemistry. 2014 Oct;106:156-163.

Chemical investigation of a sample of propolis originating from North-Western Cameroon led to the isolation of thirteen alk(en)ylphenols (1-13) (inseparable mixture) along with alpha-amyrin (14), beta-amyrin (15), lupeol (16), cycloartenol (17), mangiferonic acid (18), ambonic acid (19), Mangiferolic acid (20), ambolic acid (21), isoMangiferolic acid (22) and nine alk(en)ylresorcinols (23-31) (inseparable mixture). All compounds were identified following analysis of their spectroscopic data and comparison with previously published reports. Compounds (8), (12), (13) and (30) are new natural products. GC-MS analysis carried out on the alk(en)ylphenol and alk(en)ylresorcinol mixtures (dimethyl disulphide trimethylsilyl derivatives) revealed the presence of saturated and mono-unsaturated compounds with side chain lengths ranging from C11 to C19 and C15 to C19, respectively. The position of the double bond in mono-unsaturated derivatives was established from the characteristic fragments resulting from the cleavage of the bond between the two methylthio-substituted carbons. The most abundant compound in each mixture was 3-(12'Z-heptadecenyl)-phenol (10) and 5-(12'Z-heptadecenyl)-resorcinol (29). This study is the first to report the presence of triterpenes (except for lupeol) and phenolic lipids, including eighteen compounds previously unreported in bee glue, in an African sample.

[Triterpene acids from the barks of Illicium difengpi].[Pubmed:11596298]

Yao Xue Xue Bao. 1997 Sep;32(9):704-7.

Four compounds were isolated from the traditional Chinese medicine "Difengpi", barks of Illicium difengpi K.I.B. et K.I.M. They were identified as 3 beta-O-acetyl-Mangiferolic acid (I), mangiferonic acid (II), Mangiferolic acid (III) and butulinic acid (IV) by physico-chemical constants and spectral analyses (UV, IR, EIMS, 1HNMR, 13CNMR, NOEDE and 2D NMR). Compound I is a new compound. These triterpene acids (I-IV) were isolated from Illicium genus for the first time.

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