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4-Methoxysalicylic acid

CAS# 2237-36-7

4-Methoxysalicylic acid

2D Structure

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Quality Control of 4-Methoxysalicylic acid

3D structure

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4-Methoxysalicylic acid

Number of papers citing our products

Chemical Properties of 4-Methoxysalicylic acid

Cas No. 2237-36-7 SDF Download SDF
PubChem ID 75231 Appearance Powder
Formula C8H8O4 M.Wt 168.14
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-hydroxy-4-methoxybenzoic acid
SMILES COC1=CC(=C(C=C1)C(=O)O)O
Standard InChIKey MRIXVKKOHPQOFK-UHFFFAOYSA-N
Standard InChI InChI=1S/C8H8O4/c1-12-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1H3,(H,10,11)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 4-Methoxysalicylic acid

The root barks of Periploca sepium.

Biological Activity of 4-Methoxysalicylic acid

Description4-Methoxysalicylic acid is a natural product from Periploca sepium.

Protocol of 4-Methoxysalicylic acid

Structure Identification
Zhongguo Zhong Yao Za Zhi. 2007 Jul;32(13):1300-2.

Chemical constituents from root barks of Periploca sepium.[Pubmed: 17879730]

To investigate the chemical constituents of the root barks of Periploca sepium.
METHODS AND RESULTS:
Column chromatographic techniques were used to isolate the chemical constituents. NMR and MS methods were employed for their structural elucidation. Eight compounds were isolated and identified as isovanillin (1), vanillin (2), 4-Methoxysalicylic acid (3), (24R)-9, 19-cycloart-25-ene-3beta, 24-diol (4), (24S)-9, 19-cycloart-25-ene-3beta, 24-diol (5), cycloeucalenol (6), beta-amyrin acetate (7) and alpha-amyrin (8).
CONCLUSIONS:
Compounds 1-6 were isolated from this plant for the first time.

4-Methoxysalicylic acid Dilution Calculator

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4-Methoxysalicylic acid Molarity Calculator

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Preparing Stock Solutions of 4-Methoxysalicylic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.9474 mL 29.7371 mL 59.4742 mL 118.9485 mL 148.6856 mL
5 mM 1.1895 mL 5.9474 mL 11.8948 mL 23.7897 mL 29.7371 mL
10 mM 0.5947 mL 2.9737 mL 5.9474 mL 11.8948 mL 14.8686 mL
50 mM 0.1189 mL 0.5947 mL 1.1895 mL 2.379 mL 2.9737 mL
100 mM 0.0595 mL 0.2974 mL 0.5947 mL 1.1895 mL 1.4869 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 4-Methoxysalicylic acid

[Chemical constituents from root barks of Periploca sepium].[Pubmed:17879730]

Zhongguo Zhong Yao Za Zhi. 2007 Jul;32(13):1300-2.

OBJECTIVE: To investigate the chemical constituents of the root barks of Periploca sepium. METHOD: Column chromatographic techniques were used to isolate the chemical constituents. NMR and MS methods were employed for their structural elucidation. RESULT: Eight compounds were isolated and identified as isovanillin (1), vanillin (2), 4-Methoxysalicylic acid (3), (24R)-9, 19-cycloart-25-ene-3beta, 24-diol (4), (24S)-9, 19-cycloart-25-ene-3beta, 24-diol (5), cycloeucalenol (6), beta-amyrin acetate (7) and alpha-amyrin (8). CONCLUSION: Compounds 1-6 were isolated from this plant for the first time.

Description

2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker.

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