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Tiadinil

CAS# 223580-51-6

Tiadinil

2D Structure

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3D structure

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Tiadinil

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Chemical Properties of Tiadinil

Cas No. 223580-51-6 SDF Download SDF
PubChem ID 2804318 Appearance Powder
Formula C11H10ClN3OS M.Wt 267.73
Type of Compound N/A Storage Desiccate at -20°C
Synonyms AK163155
Solubility Soluble in DMSO
Chemical Name N-(3-chloro-4-methylphenyl)-4-methylthiadiazole-5-carboxamide
SMILES CC1=C(C=C(C=C1)NC(=O)C2=C(N=NS2)C)Cl
Standard InChIKey VJQYLJSMBWXGDV-UHFFFAOYSA-N
Standard InChI InChI=1S/C11H10ClN3OS/c1-6-3-4-8(5-9(6)12)13-11(16)10-7(2)14-15-17-10/h3-5H,1-2H3,(H,13,16)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Tiadinil

DescriptionTiadinil is a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles; insecticide agent.

References:
[1]. Maeda T, et al. Tiadinil, a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles that attract the predatory mite Neoseiulus womersleyi in the tea plant Camellia sinensis. Exp Appl Acarol. 2012 Nov;58( [2]. Chen X, et al. Determination of tiadinil and its metabolite in flue-cured tobacco. J Chromatogr Sci. 2014 Aug;52(7):624-8.

Tiadinil Dilution Calculator

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Preparing Stock Solutions of Tiadinil

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.7351 mL 18.6755 mL 37.3511 mL 74.7021 mL 93.3777 mL
5 mM 0.747 mL 3.7351 mL 7.4702 mL 14.9404 mL 18.6755 mL
10 mM 0.3735 mL 1.8676 mL 3.7351 mL 7.4702 mL 9.3378 mL
50 mM 0.0747 mL 0.3735 mL 0.747 mL 1.494 mL 1.8676 mL
100 mM 0.0374 mL 0.1868 mL 0.3735 mL 0.747 mL 0.9338 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on Tiadinil

Tiadinil is a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles; insecticide agent.

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References on Tiadinil

Determination of tiadinil and its metabolite in flue-cured tobacco.[Pubmed:23825350]

J Chromatogr Sci. 2014 Aug;52(7):624-8.

A novel and sensitive method was developed for the determination of residues of Tiadinil and its metabolite, 4-methyl-l,2,3-thiadiazole-5-carboxylic acid, in flue-cured tobacco. The pesticides were extracted with acetone and purified by gel permeation chromatography and solid-phase extraction. Analysis was performed by ultra-performance liquid chromatography-tandem mass spectrometry in negative ionization mode. Two precursor-product ion transitions were monitored for both compounds in the multiple reaction monitoring mode. Quantification was conducted by using matrix-matched standard calibration. Recovery values of the proposed method for Tiadinil ranged from 72.5 to 98.2%, with relative standard deviations ranging from 3.8 to 9.5%; recovery values for 4-methyl-l,2,3-thiadiazole-5-carboxylic acid ranged from 75.4 to 103.3% with RSDs ranging from 3.7 to 9.3%. The limit of quantification for both compounds was 0.01 mg/kg. This method is valuable for residual analysis, quality control and monitoring of Tiadinil and its metabolite, 4-methyl-l,2,3-thiadiazole-5-carboxylic acid, in tobacco.

Tiadinil, a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles that attract the predatory mite Neoseiulus womersleyi in the tea plant Camellia sinensis.[Pubmed:22669277]

Exp Appl Acarol. 2012 Nov;58(3):247-58.

Plants respond with various defense mechanisms to pathogenic or herbivorous attack. Some chemicals called plant activators that induce the plant defense response against pathogens have been commercially used to protect plants. Here we studied the effects of Tiadinil (TDL) on defense mechanisms against herbivores. TDL suppresses pathogenic fungi on tea leaves by inducing defense mechanisms. We used one of the major trophic systems in tea consisting of the herbivorous mite, Tetranychus kanzawai, and the predatory mite, Neoseiulus womersleyi. TDL enhanced the production of herbivore-induced plant volatiles that attract predatory mites. The predatory mites preferred the T. kanzawai-induced volatiles from TDL-treated plants to those produced by untreated plants. These results suggest that TDL activates the plant defense response via an indirect process mediated by plant volatiles that attract natural enemies of the herbivores. In contrast, the oviposition rate, adult maturation rate, and sex ratio of T. kanzawai were not affected by TDL treatment. These results suggest that TDL did not activate any direct defense against the herbivorous mite.

Description

Tiadinil is a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles; fungicide.

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