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9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid

CAS# 116499-73-1

9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid

2D Structure

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9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid: 5mg $828 In Stock
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3D structure

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9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid

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Chemical Properties of 9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid

Cas No. 116499-73-1 SDF Download SDF
PubChem ID 46230361 Appearance Powder
Formula C20H30O4 M.Wt 334.45
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,2S,6R,7R,12R)-2,6-dimethyl-12-propan-2-yl-13,14-dioxatetracyclo[10.2.2.01,10.02,7]hexadec-10-ene-6-carboxylic acid
SMILES CC(C)C12CCC3(C(=C1)CCC4C3(CCCC4(C)C(=O)O)C)OO2
Standard InChIKey OOHFJWCHEFCJDC-AXDKOMKPSA-N
Standard InChI InChI=1S/C20H30O4/c1-13(2)19-10-11-20(24-23-19)14(12-19)6-7-15-17(3,16(21)22)8-5-9-18(15,20)4/h12-13,15H,5-11H2,1-4H3,(H,21,22)/t15-,17+,18-,19-,20+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid

The herbs of Cedrus deodara

Biological Activity of 9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid

Description1. 9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid shows potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate.

9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid Dilution Calculator

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Preparing Stock Solutions of 9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.99 mL 14.9499 mL 29.8998 mL 59.7997 mL 74.7496 mL
5 mM 0.598 mL 2.99 mL 5.98 mL 11.9599 mL 14.9499 mL
10 mM 0.299 mL 1.495 mL 2.99 mL 5.98 mL 7.475 mL
50 mM 0.0598 mL 0.299 mL 0.598 mL 1.196 mL 1.495 mL
100 mM 0.0299 mL 0.1495 mL 0.299 mL 0.598 mL 0.7475 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid

Potential antitumor-promoting diterpenoids from the stem bark of Picea glehni.[Pubmed:10869208]

J Nat Prod. 2000 Jun;63(6):817-20.

A novel rearranged labdane-type diterpenoid, 19(4-->3)abeo-8alpha, 13(S)-epoxylabda-4(18),14-diene (1), and two new abietane-type diterpenoids, 19-nor-abieta-4(18),8,11,13-tetraen-7-one (2) and 12-hydroxydehydroabietic acid (3) were isolated from the stem bark of Picea glehni, together with seven known diterpenoids-13-epimanoyl oxide (4), dehydroabietic acid (5), (11E)-14, 15-bisnor-8alpha-hydroxy-11-labden-13-one (6), abieta-8,11, 13-trien-7-one (7), 9alpha,13alpha-Epidioxyabiet-8(14)-en-18-oic acid (8), 9,10alpha-epoxy-9,10-seco-abieta-8,11,13-trien-18-oic acid (9), and methyl 15-hydroxy-7-oxo-dehydroabietate (10). Compounds 5-8 and 10 showed potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate.

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