Ac-Met-OH

CAS# 65-82-7

Ac-Met-OH

Catalog No. BCC2991----Order now to get a substantial discount!

Product Name & Size Price Stock
Ac-Met-OH: 5mg $6 In Stock
Ac-Met-OH: 10mg Please Inquire In Stock
Ac-Met-OH: 20mg Please Inquire Please Inquire
Ac-Met-OH: 50mg Please Inquire Please Inquire
Ac-Met-OH: 100mg Please Inquire Please Inquire
Ac-Met-OH: 200mg Please Inquire Please Inquire
Ac-Met-OH: 500mg Please Inquire Please Inquire
Ac-Met-OH: 1000mg Please Inquire Please Inquire
Related Products

Quality Control of Ac-Met-OH

Number of papers citing our products

Chemical structure

Ac-Met-OH

3D structure

Chemical Properties of Ac-Met-OH

Cas No. 65-82-7 SDF Download SDF
PubChem ID 448580 Appearance Powder
Formula C7H13NO3S M.Wt 191.2
Type of Compound N/A Storage Desiccate at -20°C
Synonyms N-Acetyl-L-methionine
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S)-2-acetamido-4-methylsulfanylbutanoic acid
SMILES CC(=O)NC(CCSC)C(=O)O
Standard InChIKey XUYPXLNMDZIRQH-LURJTMIESA-N
Standard InChI InChI=1S/C7H13NO3S/c1-5(9)8-6(7(10)11)3-4-12-2/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)/t6-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Ac-Met-OH Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Ac-Met-OH Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Ac-Met-OH

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.2301 mL 26.1506 mL 52.3013 mL 104.6025 mL 130.7531 mL
5 mM 1.046 mL 5.2301 mL 10.4603 mL 20.9205 mL 26.1506 mL
10 mM 0.523 mL 2.6151 mL 5.2301 mL 10.4603 mL 13.0753 mL
50 mM 0.1046 mL 0.523 mL 1.046 mL 2.0921 mL 2.6151 mL
100 mM 0.0523 mL 0.2615 mL 0.523 mL 1.046 mL 1.3075 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University

Background on Ac-Met-OH

Ac-Met-OH

Featured Products
New Products
 

References on Ac-Met-OH

Cisplatin mediates selective downstream hydrolytic cleavage of Met-(Gly)(n)-His segments (n=1,2) in methionine- and histidine-containing peptides: the role of ammine loss trans to the initial Pt-S(Met) anchor in facilitating amide hydrolysis.[Pubmed:16806482]

J Inorg Biochem. 2006 Sep;100(9):1506-13.

The pH- and time-dependent reactions of the antitumor drug cisplatin, cis-[PtCl(2)(NH(3))(2)], with the methionine- and histidine-containing pentapeptides Ac-Met-Gly-His-Gly-Gly-OH, Ac-Met-Gly-Gly-His-Gly-OH and Ac-Gly-Met-Gly-His-Gly-OH (Gly=glycyl, Met=L-methionyl, His=L-histidyl) at 313K have been investigated by high performance liquid chromatography, mass spectrometry and nuclear magnetic resonance. Cisplatin mediates a rapid "downstream" hydrolytic cleavage of the Met-Gly amide bond in weakly acid solution (pH < or =5) for all three peptides, leading to release of H-Gly-His-Gly-Gly-OH, H-Gly-Gly-His-Gly-OH and H-Gly-His-Gly-OH, respectively, and formation of kappa(2)S,N(M) chelate complexes of the methionine-containing residuals Ac-Met-OH or Ac-Gly-Met-OH. An alternative reaction pathway affords tridentate kappa(3)S,N(M),N(imidazole) macrochelates of the original pentapeptide following ammine loss. The downstream cleavage pathway is competitive with the likewise cisplatin-mediated upstream cleavage of the Ac-Gly linkage in the pentapeptide Ac-Gly-Met-Gly-His-Gly-OH. This leads to formation of both the kappa(3)S,N(M),N(G1) complex of H-Gly-Met-Gly-His-Gly-OH due to upstream cleavage and the analogous tridentate complex for H-Gly-Met-OH due to initial downstream loss of H-Gly-His-Gly-OH followed by upstream loss of acetic acid. As downstream cleavage is not observed for Ac-(Gly)(2)-Met-(Gly)(2)-OH under similar conditions, it may be concluded that rapid histidine imidazole substitution of the ammine ligand in trans-position to an anchoring methionine S atom must assist hydrolytic cleavage of the Met-Gly amide bond.

Description

N-Acetyl-L-methionine, a human metabolite, is nutritionally and metabolically equivalent to L-methionine. L-methionine is an indispensable amino acid required for normal growth and development.

Keywords:

Ac-Met-OH,65-82-7,N-Acetyl-L-methionine,Natural Products,Amino Acids and Derivatives, buy Ac-Met-OH , Ac-Met-OH supplier , purchase Ac-Met-OH , Ac-Met-OH cost , Ac-Met-OH manufacturer , order Ac-Met-OH , high purity Ac-Met-OH

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: