Alboctalol

CAS# 62394-00-7

Alboctalol

2D Structure

Catalog No. BCN4158----Order now to get a substantial discount!

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Alboctalol: 5mg $748 In Stock
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Quality Control of Alboctalol

3D structure

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Alboctalol

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Chemical Properties of Alboctalol

Cas No. 62394-00-7 SDF Download SDF
PubChem ID 85235974 Appearance Powder
Formula C28H24O8 M.Wt 488.5
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 6,8-bis(2,4-dihydroxyphenyl)-7-(3,5-dihydroxyphenyl)-5,6,7,8-tetrahydronaphthalene-1,3-diol
SMILES C1C(C(C(C2=C(C=C(C=C21)O)O)C3=C(C=C(C=C3)O)O)C4=CC(=CC(=C4)O)O)C5=C(C=C(C=C5)O)O
Standard InChIKey QQGGCAFWTCETPD-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Alboctalol

The herbs of Cudrania tricuspidata

Biological Activity of Alboctalol

Description1. Alboctalol inhibits mushroom tyrosinase activity.

Alboctalol Dilution Calculator

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Alboctalol Molarity Calculator

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Preparing Stock Solutions of Alboctalol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0471 mL 10.2354 mL 20.4708 mL 40.9417 mL 51.1771 mL
5 mM 0.4094 mL 2.0471 mL 4.0942 mL 8.1883 mL 10.2354 mL
10 mM 0.2047 mL 1.0235 mL 2.0471 mL 4.0942 mL 5.1177 mL
50 mM 0.0409 mL 0.2047 mL 0.4094 mL 0.8188 mL 1.0235 mL
100 mM 0.0205 mL 0.1024 mL 0.2047 mL 0.4094 mL 0.5118 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Alboctalol

Secondary metabolites of Bagassa guianensis Aubl. wood: a study of the chemotaxonomy of the Moraceae family.[Pubmed:20655556]

Phytochemistry. 2010 Oct;71(14-15):1708-13.

In order to explain the durability of the Moraceae plant family, phytochemistry of Bagassa guianensis was performed. Ethyl acetate extract was obtained from the heartwood and 18 secondary metabolites were isolated, including 6 moracins [6-O-methyl-moracin M, 6-O-methyl-moracin N and moracin Z; previously identified: moracin M, moracin N and moracin P], 8 stilbenoids [presently identified: (-)-epiAlboctalol and arachidin 4; previously identified: Alboctalol, trans-resveratrol, arachidin 2, trans-oxyresveratrol and artogomezianol], 3 previously identified flavonoids, steppogenin, katuranin and dihydromorin, beta-sitosterol and resorcinol. Previous studies suggest that stilbenoids are responsible for the natural durability of wood. Our study has determined that B. guianensis is closely related to Morus sp. in phylogeny and should be included in the Moreae sensu stricto tribe of the Moraceae family.

Chemical constituents derived from Artocarpus xanthocarpus as inhibitors of melanin biosynthesis.[Pubmed:26188915]

Phytochemistry. 2015 Sep;117:424-435.

Twenty-four compounds, including the previously unknown artoxanthocarpuone A, artoxanthocarpuone B, hydroxylakoochin A, methoxylakoochin A, epoxylakoochin A, and artoxanthol, were isolated and characterized spectroscopically. Among them, artoxanthol is stilbene oligomer presumably constructed in a 5,11,12-triphenyl hexahydrochrysene scaffold by a Diels-Alder type of reaction, for which a biosynthetic pathway is proposed. Artoxanthol, Alboctalol, steppogenin, norartocarpetin, resveratrol, oxyresveratrol, and chlorophorin potently inhibited mushroom tyrosinase activity with IC50 values from 0.9 to 5.7 muM that were all far stronger than the positive controls. Artoxanthocarpuone A, artoxanthocarpuone B, methoxylakoochin A, lakoochin A, cudraflavone C, artonin A, resveratrol, and chlorophorin reduced tyrosinase activity and inhibited alpha-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells without affecting cell proliferation. Collectively, the results suggest that the constituents of Artocarpus xanthocarpus have potential to be used as depigmentation agents.

Phenolic constituents from the wood of Morus australis with cytotoxic activity.[Pubmed:18386485]

Z Naturforsch C. 2008 Jan-Feb;63(1-2):35-9.

A new methylated flavonol, 5,7,2',4'-tetrahydroxy-3-methoxyflavone (1), had been isolated from the methanol extract of the wood of Morus australis, along with nine known compounds, kuwanon C (2), morusin (3), morachalcone A (4), oxyresveratrol (5), 4'-(2-methyl-2-buten-4-yl)oxyresveratrol (6), moracins M (7) and C (8), Alboctalol (9), and macrourin B (10). The structures of these compounds were determined based on spectral evidence, including UV, IR, NMR, and mass spectra. Cytotoxic properties of compounds 1-10 were evaluated against murine leukemia P-388 cells. The prenylated stilbene 6 and 2-arylbenzofuran 8, and morusin (3) were found to have strong cytotoxic effects with IC50 values of 6.9, 8.7, and 10.1 microM, respectively.

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