Alpinin ACAS# 2151847-03-7 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
| Cas No. | 2151847-03-7 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C20H24O7 | M.Wt | 376.4 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Alpinin A Dilution Calculator
Alpinin A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6567 mL | 13.2837 mL | 26.5675 mL | 53.135 mL | 66.4187 mL |
| 5 mM | 0.5313 mL | 2.6567 mL | 5.3135 mL | 10.627 mL | 13.2837 mL |
| 10 mM | 0.2657 mL | 1.3284 mL | 2.6567 mL | 5.3135 mL | 6.6419 mL |
| 50 mM | 0.0531 mL | 0.2657 mL | 0.5313 mL | 1.0627 mL | 1.3284 mL |
| 100 mM | 0.0266 mL | 0.1328 mL | 0.2657 mL | 0.5313 mL | 0.6642 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Diarylheptanoids from Rhizomes of Alpinia officinarum Inhibit Aggregation of alpha-Synuclein.[Pubmed:28707886]
J Agric Food Chem. 2017 Aug 9;65(31):6608-6614.
Two new diarylheptanoids, Alpinin A (1) and alpinin B (2), together with 18 known diarylheptanoids (3-20), were isolated from the rhizomes of Alpinia officinarum. Their structures were elucidated by comprehensive spectroscopic analysis, including high-resolution mass spectrometry, infrared spectroscopy, and one- and two-dimensional nuclear magnetic resonance spectroscopy. Structurally, Alpinin A is a new member of the small family of oxa-bridged diarylheptanoids and contains the characteristic 2,6-cis-configured tetrahydropyran motif (C1-C5 oxa bridge). The absolute configuration of Alpinin A was confirmed by asymmetric total synthesis of the enantiomer (ent-1), corroborating the assignment of the molecular structure. The absolute configuration of alpinin B was determined on the basis of the analysis of the circular dichroism exciton chirality spectrum. We evaluated the inhibitory activity of all isolated diarylheptanoids against alpha-synuclein aggregation at 10 muM. Alpinins A and B significantly inhibited alpha-synuclein aggregation by 66 and 67%, respectively.
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