Ascleposide E

CAS# 325686-49-5

Ascleposide E

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Quality Control of Ascleposide E

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Chemical structure

Ascleposide E

3D structure

Chemical Properties of Ascleposide E

Cas No. 325686-49-5 SDF Download SDF
PubChem ID 102004450 Appearance Powder
Formula C19H32O8 M.Wt 388.5
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-[(3S,8R)-1,5-dimethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-oxabicyclo[3.2.1]octan-8-yl]butan-2-one
SMILES CC(=O)CCC1C2(CC(CC1(OC2)C)OC3C(C(C(C(O3)CO)O)O)O)C
Standard InChIKey FUGMJWOONJABQQ-UBHNRPOQSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ascleposide E

The roots of Aucklandia lappa Decne

Protocol of Ascleposide E

Structure Identification
Zhongguo Zhong Yao Za Zhi. 2012 May;37(9):1232-6.

Chemical constituents from a portion of ethanolicextract of Saussurea lappa roots.[Pubmed: 22803366]

To study chemical constituents from the roots of Saussurea lappa.
METHODS AND RESULTS:
Chemical constituents were separated and purified by various techniques such as silica gel column chromatography, Sephadex LH-20 and reversed phase RP-18 column chromatography. Their structures were identified on the basis of spectral data. Seventeen compounds were separated and identified as Ascleposide E(1), (+)-1-hydroxypinoresinol-4"-O-methyl ester-4'-beta-D-glucopyranoside (2), (+)-1 -hydroxypinoresinol-4"-O-beta-D-glucopyranoside(3), (+)-1-hydroxypinoresinol-1-O-P-D-glucopyranoside (4), phenyl-beta-D-glucopyranoside (5), benzyl-beta-D-glucopyranoside (6), n-butyl-beta-D-glucopyranoside (7), ilicic alcohol (8), beta-cyclocostunolide (9), reynosin (10), 11beta, 13-dihydroreynosin (11), arbusculin A(12), 1beta-hydroxy-arbusculin A (13), santamarin (14), dehydrocostuslactone (15), 11beta, 13-dihydro-3-epizaluzanin C(16)and costunolide (17).
CONCLUSIONS:
Compounds 1-2 were separated from this genus for the first time,and compounds 3,5-7 were separated from this plant for the first time.

Ascleposide E Dilution Calculator

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Ascleposide E Molarity Calculator

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Preparing Stock Solutions of Ascleposide E

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.574 mL 12.87 mL 25.74 mL 51.4801 mL 64.3501 mL
5 mM 0.5148 mL 2.574 mL 5.148 mL 10.296 mL 12.87 mL
10 mM 0.2574 mL 1.287 mL 2.574 mL 5.148 mL 6.435 mL
50 mM 0.0515 mL 0.2574 mL 0.5148 mL 1.0296 mL 1.287 mL
100 mM 0.0257 mL 0.1287 mL 0.2574 mL 0.5148 mL 0.6435 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ascleposide E

[Chemical constituents from a portion of ethanolicextract of Saussurea lappa roots].[Pubmed:22803366]

Zhongguo Zhong Yao Za Zhi. 2012 May;37(9):1232-6.

OBJECTIVE: To study chemical constituents from the roots of Saussurea lappa. METHOD: Chemical constituents were separated and purified by various techniques such as silica gel column chromatography, Sephadex LH-20 and reversed phase RP-18 column chromatography. Their structures were identified on the basis of spectral data. RESULT: Seventeen compounds were separated and identified as Ascleposide E(1), (+)-1-hydroxypinoresinol-4"-O-methyl ester-4'-beta-D-glucopyranoside (2), (+)-1 -hydroxypinoresinol-4"-O-beta-D-glucopyranoside(3), (+)-1-hydroxypinoresinol-1-O-P-D-glucopyranoside (4), phenyl-beta-D-glucopyranoside (5), benzyl-beta-D-glucopyranoside (6), n-butyl-beta-D-glucopyranoside (7), ilicic alcohol (8), beta-cyclocostunolide (9), reynosin (10), 11beta, 13-dihydroreynosin (11), arbusculin A(12), 1beta-hydroxy-arbusculin A (13), santamarin (14), dehydrocostuslactone (15), 11beta, 13-dihydro-3-epizaluzanin C(16)and costunolide (17). CONCLUSION: Compounds 1-2 were separated from this genus for the first time,and compounds 3,5-7 were separated from this plant for the first time.

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