Axinysone B

CAS# 1114491-60-9

Axinysone B

Catalog No. BCN7713----Order now to get a substantial discount!

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Axinysone B: 5mg $851 In Stock
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Quality Control of Axinysone B

Number of papers citing our products

Chemical structure

Axinysone B

3D structure

Chemical Properties of Axinysone B

Cas No. 1114491-60-9 SDF Download SDF
PubChem ID 23928099 Appearance Powder
Formula C15H22O2 M.Wt 234.33
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1aR,4S,7R,7aR,7bS)-4-hydroxy-1,1,7,7a-tetramethyl-1a,4,5,6,7,7b-hexahydrocyclopropa[a]naphthalen-2-one
SMILES CC1CCC(C2=CC(=O)C3C(C12C)C3(C)C)O
Standard InChIKey KDPNSOLPHGZUAY-WHOUDRSTSA-N
Standard InChI InChI=1S/C15H22O2/c1-8-5-6-10(16)9-7-11(17)12-13(14(12,2)3)15(8,9)4/h7-8,10,12-13,16H,5-6H2,1-4H3/t8-,10+,12-,13+,15+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Axinysone B

The metabolites of the mushroom Anthracophyllum sp. BCC18695.

Biological Activity of Axinysone B

DescriptionAxinysone B is a natiral product from the metabolites of the mushroom Anthracophyllum sp. BCC18695.
In vitro

New bioactive secondary metabolites from Bornean red alga, Laurencia similis (Ceramiales).[Pubmed: 23678792]

Nat Prod Commun. 2013 Mar;8(3):287-8.


METHODS AND RESULTS:
A Bomean red algal population of Laurencia similis Nam et Saito was analyzed for its secondary metabolite composition. Seven compounds were identified: ent-1(10)-aristolen-9beta-ol (1), (+)-aristolone (2), Axinysone B (3), 9-aristolen-1alpha-ol (4), 2,3,5,6-tetrabromoindole (5), 1-methyl-2,3,5,6-tetrabromoindole (6), and 1-methyl-2,3,5-tribromoindole (7). Compound 1 was identified as a new optical isomer of 1(10)-aristolen-9beta-ol.
CONCLUSIONS:
Compounds 1, 4 and 5 exhibited good antibacterial activity against antibiotic resistant clinical bacteria and cytotoxic effects against selected cancer cell lines.

Novel spiro-sesquiterpene from the mushroom Anthracophyllum sp. BCC18695[Reference: WebLink]

Phytochemistry Letters, 2013, 6(3):345-349.


METHODS AND RESULTS:
A novel spiro-sesquiterpene, anthracophyllic acid (1), and a new aristolane sesquiterpene, anthracophyllone (2), were isolated from the mushroom Anthracophyllum sp. BCC18695, together with seven known compounds including aurisins A (3), G (4), K (5), nambinone A, nambinone C, axinysone A, and Axinysone B. The relative configuration of 1 and the hitherto unknown absolute stereochemistry of 3 were determined based on X-ray spectroscopic data.
CONCLUSIONS:
Biological activities including antimalarial activity against Plasmodium falciparum K1 strain, antibacterial property against Bacillus cereus, and cytotoxicity against MCF-7, KB, NCI-H187, and Vero cells of the isolated compounds were also evaluated.

Axinysone B Dilution Calculator

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Axinysone B Molarity Calculator

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Preparing Stock Solutions of Axinysone B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.2675 mL 21.3374 mL 42.6749 mL 85.3497 mL 106.6872 mL
5 mM 0.8535 mL 4.2675 mL 8.535 mL 17.0699 mL 21.3374 mL
10 mM 0.4267 mL 2.1337 mL 4.2675 mL 8.535 mL 10.6687 mL
50 mM 0.0853 mL 0.4267 mL 0.8535 mL 1.707 mL 2.1337 mL
100 mM 0.0427 mL 0.2134 mL 0.4267 mL 0.8535 mL 1.0669 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Axinysone B

New bioactive secondary metabolites from Bornean red alga, Laurencia similis (Ceramiales).[Pubmed:23678792]

Nat Prod Commun. 2013 Mar;8(3):287-8.

A Bomean red algal population of Laurencia similis Nam et Saito was analyzed for its secondary metabolite composition. Seven compounds were identified: ent-1(10)-aristolen-9beta-ol (1), (+)-aristolone (2), Axinysone B (3), 9-aristolen-1alpha-ol (4), 2,3,5,6-tetrabromoindole (5), 1-methyl-2,3,5,6-tetrabromoindole (6), and 1-methyl-2,3,5-tribromoindole (7). Compound 1 was identified as a new optical isomer of 1(10)-aristolen-9beta-ol. Compounds 1, 4 and 5 exhibited good antibacterial activity against antibiotic resistant clinical bacteria and cytotoxic effects against selected cancer cell lines.

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