Bullatine B

CAS# 466-26-2

Bullatine B

Catalog No. BCN2375----Order now to get a substantial discount!

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Quality Control of Bullatine B

Number of papers citing our products

Chemical structure

Bullatine B

3D structure

Chemical Properties of Bullatine B

Cas No. 466-26-2 SDF Download SDF
PubChem ID 120682 Appearance Powder
Formula C24H39NO6 M.Wt 437.6
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CCN1CC2(CCC(C34C2C(C(C31)C5(CC(C6CC4C5C6O)OC)O)OC)O)COC
Standard InChIKey XRARAKHBJHWUHW-UHFFFAOYSA-N
Standard InChI InChI=1S/C24H39NO6/c1-5-25-10-22(11-29-2)7-6-15(26)24-13-8-12-14(30-3)9-23(28,16(13)18(12)27)17(21(24)25)19(31-4)20(22)24/h12-21,26-28H,5-11H2,1-4H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Bullatine B

The roots of Aconitum brachypodum Diels

Protocol of Bullatine B

Structure Identification
Acta Chimica Sinica, 1980(05):475-480.

STUDIES ON THE CHINESE DRUG, ACONITUM SPP Ⅻ. ALKALOIDS FROM XUAN-WU, ACONITUM NAGARUM STAPF VAR. LASIANDRUM W. T. WANG.[Reference: WebLink]


METHODS AND RESULTS:
Four crystalline alkaloids Xuan-Wu 1, 2, 3 and 4 have been isolated from the root of Aconitum nagarum Stapf var. lasiandrum W. T. Wang (a Chinese folk medicine). Xuan-Wu 1, 2, 3 and 4 are proved to be identical with Bullatine A, Bullatine G, Bullatine B and Bullatine C respectively by comparison of their physical constants, IR, TLC and mixed melting points.
CONCLUSIONS:
Therefore. the molecular formula of Bullatine A ought to be amended to C_(22)H_(33)O_2N and Bullatine G to C_(22)H_(31)O_3N. Furthermore, Xuan-Wu 2 and 3 have been proved to be identical with the known compounds songorine and neoline respectively and the structure of Xuan-Wu 4(i. e. Bullatine C)is proved by chemical and spectral studies to be a new compound, 14-acetylneoline.Nuan-Wu 4 has the formula C_(26)H_(41)O_7N, m. p. 198~202℃, [α]_D~(30)+42.9° (e, 1.5, chloroform). The following crystalline salts and derivative were prepared: the nitrate, m. p. 197~200℃, the perchlorate, m. p. 231~232℃ and the diacetate, m. p. 150~151℃.

Bullatine B Dilution Calculator

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Bullatine B Molarity Calculator

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Preparing Stock Solutions of Bullatine B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2852 mL 11.426 mL 22.8519 mL 45.7038 mL 57.1298 mL
5 mM 0.457 mL 2.2852 mL 4.5704 mL 9.1408 mL 11.426 mL
10 mM 0.2285 mL 1.1426 mL 2.2852 mL 4.5704 mL 5.713 mL
50 mM 0.0457 mL 0.2285 mL 0.457 mL 0.9141 mL 1.1426 mL
100 mM 0.0229 mL 0.1143 mL 0.2285 mL 0.457 mL 0.5713 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Description

Neoline, the active ingredient of processed aconite root (PA), alleviated oxaliplatin-induced peripheral neuropathy in mice. Neoline can be used as a marker compound to determine the quality of the PA products for the treatment of neuropathic pain.

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