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Choerospondin

CAS# 81202-36-0

Choerospondin

Catalog No. BCX0784----Order now to get a substantial discount!

Product Name & Size Price Stock
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Quality Control of Choerospondin

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Chemical structure

Choerospondin

3D structure

Chemical Properties of Choerospondin

Cas No. 81202-36-0 SDF Download SDF
PubChem ID 157745.0 Appearance Powder
Formula C21H22O10 M.Wt 434.39
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S)-5,7-dihydroxy-2-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one
SMILES C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)OC4C(C(C(C(O4)CO)O)O)O
Standard InChIKey KSDSYIXRWHRPMN-SFTVRKLSSA-N
Standard InChI InChI=1S/C21H22O10/c22-8-16-18(26)19(27)20(28)21(31-16)29-11-3-1-9(2-4-11)14-7-13(25)17-12(24)5-10(23)6-15(17)30-14/h1-6,14,16,18-24,26-28H,7-8H2/t14-,16+,18+,19-,20+,21+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Choerospondin Dilution Calculator

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Choerospondin Molarity Calculator

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Preparing Stock Solutions of Choerospondin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3021 mL 11.5104 mL 23.0208 mL 46.0416 mL 57.552 mL
5 mM 0.4604 mL 2.3021 mL 4.6042 mL 9.2083 mL 11.5104 mL
10 mM 0.2302 mL 1.151 mL 2.3021 mL 4.6042 mL 5.7552 mL
50 mM 0.046 mL 0.2302 mL 0.4604 mL 0.9208 mL 1.151 mL
100 mM 0.023 mL 0.1151 mL 0.2302 mL 0.4604 mL 0.5755 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Choerospondin

[Functional characterization and enzymatic properties of flavonoid glycosyltransferase gene CtUGT49 in Carthamus tinctorius].[Pubmed:38212022]

Zhongguo Zhong Yao Za Zhi. 2023 Dec;48(24):6624-6634.

Carthami Flos, as a traditional blood-activating and stasis-resolving drug, possesses anti-tumor, anti-inflammatory, and immunomodulatory pharmacological activities. Flavonoid glycosides are the main bioactive components in Carthamus tinctorius. Glycosyltransferase deserves to be studied in depth as a downstream modification enzyme in the biosynthesis of active glycoside compounds. This study reported a flavonoid glycosyltransferase CtUGT49 from C. tinctorius based on the transcriptome data, followed by bioinformatic analysis and the investigation of enzymatic properties. The open reading frame(ORF) of the gene was 1 416 bp, encoding 471 amino acid residues with the molecular weight of about 52 kDa. Phylogenetic analysis showed that CtUGT49 belonged to the UGT73 family. According to in vitro enzymatic results, CtUGT49 could catalyze naringenin chalcone to the prunin and Choerospondin, and catalyze phloretin to phlorizin and trilobatin, exhibiting good substrate versatility. After the recombinant protein CtUGT49 was obtained by hetero-logous expression and purification, the enzymatic properties of CtUGT49 catalyzing the formation of prunin from naringenin chalcone were investigated. The results showed that the optimal pH value for CtUGT49 catalysis was 7.0, the optimal temperature was 37 ℃, and the highest substrate conversion rate was achieved after 8 h of reaction. The results of enzymatic kinetic parameters showed that the K_m value was 209.90 mumol.L~(-1) and k_(cat) was 48.36 s~(-1) calculated with the method of Michaelis-Menten plot. The discovery of the novel glycosyltransferase CtUGT49 is important for enriching the library of glycosylation tool enzymes and provides a basis for analyzing the glycosylation process of flavonoid glycosides in C. tinctorius.

[Chemical Constituents from Cynomorium songaricum].[Pubmed:30079707]

Zhong Yao Cai. 2016 Jan;39(1):74-7.

OBJECTIVE: To study the chemical constituents from the fleshy stems of Cynomorium songaricum. METHODS: The chemical constituents were isolated and purified by chromatography on MCI, silica gel, Sephadex LH-20 columns, etc. The structures of compounds were elucidated by physicochemical property and spectral analyses. RESULTS: 15 compounds were isolated and identified as Choerospondin( 1), isolariciresinol-4-O-beta-D-glucopyranoside( 2), lutelin-7-O-beta-D-glucopyranoside( 3), 3, 4-dihydroxyphenethylacetate( 4),maslinic acid( 5),catechin ( 6),ursolic acid( 7),gentisic acid( 8),mannitol( 9), phloroglucinol( 10), beta-sitosterol( 11), daucosterol( 12), rutin( 13), cetylic acid( 14) and epicatechin( 15). CONCLUSION: Compounds 4,5,8,9 and 10 are obtained from this plant for the first time.

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